Identity
HGNC
LOCATION
15q22.31
LOCUSID
ALIAS
HsT17379,VPS5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6642
MIM: 601272
HGNC: 11172
Ensembl: ENSG00000028528
Variants:
dbSNP: 6642
ClinVar: 6642
TCGA: ENSG00000028528
COSMIC: SNX1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38836326 | 2024 | Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells. | 0 |
| 38836326 | 2024 | Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1/2 in HCT116 colorectal cancer cells. | 0 |
| 34866035 | 2022 | Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. | 7 |
| 34866035 | 2022 | Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. | 7 |
| 32293069 | 2020 | Sorting nexin 1 loss results in increased oxidative stress and hypertension. | 5 |
| 32293069 | 2020 | Sorting nexin 1 loss results in increased oxidative stress and hypertension. | 5 |
| 29284659 | 2018 | A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells. | 19 |
| 29284659 | 2018 | A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells. | 19 |
| 26643894 | 2016 | Down-regulation of SNX1 predicts poor prognosis and contributes to drug resistance in colorectal cancer. | 10 |
| 26643894 | 2016 | Down-regulation of SNX1 predicts poor prognosis and contributes to drug resistance in colorectal cancer. | 10 |
| 25653196 | 2015 | EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line. | 23 |
| 25653196 | 2015 | EGF‑stimulated AKT activation is mediated by EGFR recycling via an early endocytic pathway in a gefitinib‑resistant human lung cancer cell line. | 23 |
| 24835695 | 2014 | MiR-95 induces proliferation and chemo- or radioresistance through directly targeting sorting nexin1 (SNX1) in non-small cell lung cancer. | 17 |
| 24835695 | 2014 | MiR-95 induces proliferation and chemo- or radioresistance through directly targeting sorting nexin1 (SNX1) in non-small cell lung cancer. | 17 |
| 23152498 | 2013 | Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice. | 23 |
Citation
Dessen P
SNX1 (sorting nexin 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49891/snx1
