SNX12 (sorting nexin 12)

2014-11-01  

Identity

HGNC
SNX12
LOCATION
Xq13.1
LOCUSID
29934
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29934
MIM: 300883
HGNC: 14976
Ensembl: ENSG00000147164

Variants:

dbSNP: 29934
ClinVar: 29934
TCGA: ENSG00000147164
COSMIC: SNX12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147164ENST00000276105Q9UMY4
ENSG00000147164ENST00000374274Q9UMY4
ENSG00000147164ENST00000374274Q3SYF1
ENSG00000147164ENST00000622259A0A087X0R6
ENSG00000147164ENST00000622277Q9UMY4
ENSG00000147164ENST00000622277Q3SYF1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
161667382006The role of metallothionein in the pathogenesis of acute lung injury.24
227094162012Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.19
227199972012SNX12 role in endosome membrane transport.6
287058362017Essential and selective role of SNX12 in transport of endocytic and retrograde cargo.2

Citation

Dessen P

SNX12 (sorting nexin 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74046/snx12