Identity
HGNC
LOCATION
1q25.2
LOCUSID
ALIAS
ACACT,ACAT,ACAT-1,ACAT1,SOAT,STAT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6646
MIM: 102642
HGNC: 11177
Ensembl: ENSG00000057252
Variants:
dbSNP: 6646
ClinVar: 6646
TCGA: ENSG00000057252
COSMIC: SOAT1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000057252 | ENST00000367619 | P35610 |
| ENSG00000057252 | ENST00000426956 | B1APM4 |
| ENSG00000057252 | ENST00000539888 | P35610 |
| ENSG00000057252 | ENST00000540564 | P35610 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38673803 | 2024 | Sterol O-Acyltransferase 1 (SOAT1): A Genetic Modifier of Niemann-Pick Disease, Type C1. | 0 |
| 38724499 | 2024 | SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma. | 0 |
| 38770938 | 2024 | SOAT1 in gallbladder cancer: Clinicopathological significance and avasimibe therapeutics. | 0 |
| 38673803 | 2024 | Sterol O-Acyltransferase 1 (SOAT1): A Genetic Modifier of Niemann-Pick Disease, Type C1. | 0 |
| 38724499 | 2024 | SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma. | 0 |
| 38770938 | 2024 | SOAT1 in gallbladder cancer: Clinicopathological significance and avasimibe therapeutics. | 0 |
| 34326474 | 2022 | High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer. | 9 |
| 34460058 | 2022 | SOAT1 is a new prognostic factor of colorectal cancer. | 2 |
| 34670102 | 2022 | SOAT1 enhances lung cancer invasiveness by stimulating AKT-mediated mitochondrial fragmentation. | 6 |
| 35354120 | 2022 | piRNA-6426 increases DNMT3B-mediated SOAT1 methylation and improves heart failure. | 9 |
| 35409086 | 2022 | SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma? | 6 |
| 35941608 | 2022 | High-affinity SOAT1 ligands remodeled cholesterol metabolism program to inhibit tumor growth. | 7 |
| 34326474 | 2022 | High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer. | 9 |
| 34460058 | 2022 | SOAT1 is a new prognostic factor of colorectal cancer. | 2 |
| 34670102 | 2022 | SOAT1 enhances lung cancer invasiveness by stimulating AKT-mediated mitochondrial fragmentation. | 6 |
Citation
Dessen P
SOAT1 (sterol O-acyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43926/soat1
