Identity
HGNC
LOCATION
21q22.11
LOCUSID
ALIAS
ALS,ALS1,HEL-S-44,IPOA,SOD,STAHP,hSod1,homodimer
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6647
MIM: 147450
HGNC: 11179
Ensembl: ENSG00000142168
Variants:
dbSNP: 6647
ClinVar: 6647
TCGA: ENSG00000142168
COSMIC: SOD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142168 | ENST00000270142 | P00441 |
| ENSG00000142168 | ENST00000270142 | V9HWC9 |
| ENSG00000142168 | ENST00000389995 | H7BYH4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37930481 | 2024 | Unveiling the SOD1-mediated ALS phenotype: insights from a comprehensive meta-analysis. | 2 |
| 37988788 | 2024 | Unveiling local and global conformational changes and allosteric communications in SOD1 systems using molecular dynamics simulation and network analyses. | 0 |
| 38040051 | 2024 | Impact of a 50bp insertion/deletion polymorphism of the superoxide dismutase-1 on oxidative stress status and risk of keratoconus. | 1 |
| 38056310 | 2024 | ALS-linked SOD1 mutations impair mitochondrial-derived vesicle formation and accelerate aging. | 2 |
| 38165347 | 2024 | Observing Patterns in MRI With QSM in Patients With SOD1 Genetic ALS (5047). | 0 |
| 38285782 | 2024 | Superoxide Dismutase (rs2070424, rs4880, rs2536512) and Catalase (rs794316, rs1001179) SNPs and their Association with Breast Cancer Risk: Findings from a Hospital Based Case-Control Study. | 0 |
| 38522514 | 2024 | Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1. | 0 |
| 38567607 | 2024 | Association of SOD1 gene variants (50 bp Ins/Del, rs4817415, rs2070424, rs1041740, rs17880135) with plasma protein levels in vitiligo patients and their analysis in silico. | 0 |
| 38568044 | 2024 | High Frequency of Cognitive and Behavioral Impairment in Amyotrophic Lateral Sclerosis Patients with SOD1 Pathogenic Variants. | 0 |
| 38657911 | 2024 | Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome aberrations. | 0 |
| 38835240 | 2024 | Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells. | 1 |
| 38896450 | 2024 | SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells. | 1 |
| 37930481 | 2024 | Unveiling the SOD1-mediated ALS phenotype: insights from a comprehensive meta-analysis. | 2 |
| 37988788 | 2024 | Unveiling local and global conformational changes and allosteric communications in SOD1 systems using molecular dynamics simulation and network analyses. | 0 |
| 38040051 | 2024 | Impact of a 50bp insertion/deletion polymorphism of the superoxide dismutase-1 on oxidative stress status and risk of keratoconus. | 1 |
Citation
Dessen P
SOD1 (superoxide dismutase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/42352/sod1
