SOX2-OT (SOX2 overlapping transcript)

2014-08-01  

Identity

HGNC
LOCATION
3q26.33
LOCUSID
ALIAS
NCRNA00043,SOX2OT
FUSION GENES

Other Information

Locus ID:

NCBI: 347689
MIM: 616338
HGNC: 20209
Ensembl: ENSG00000242808

Variants:

dbSNP: 347689
ClinVar: 347689
TCGA: ENSG00000242808
COSMIC: SOX2-OT

RNA/Proteins

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
241059292014Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and OCT4 in esophageal squamous cell carcinoma.53
289607572017LncRNA SOX2-OT is a novel prognostic biomarker for osteosarcoma patients and regulates osteosarcoma cells proliferation and motility through modulating SOX2.16
288672472017Yin Yang-1 suppresses pancreatic ductal adenocarcinoma cell proliferation and tumor growth by regulating SOX2OT-SOX2 axis.12
297828282018Long noncoding RNA SOX2OT contributes to gastric cancer progression by sponging miR-194-5p from AKT2.12
267033822016Identification of new SOX2OT transcript variants highly expressed in human cancer cell lines and down regulated in stem cell differentiation.6
305568552018IRF4-induced upregulation of lncRNA SOX2-OT promotes cell proliferation and metastasis in cholangiocarcinoma by regulating SOX2 and PI3K/AKT signaling.6
308118702019Long noncoding RNA SOX2-OT facilitates laryngeal squamous cell carcinoma development by epigenetically inhibiting PTEN via methyltransferase EZH2.4
313013072019LncRNA SOX2OT alleviates the high glucose-induced podocytes injury through autophagy induction by the miR-9/SIRT1 axis.2
249279022014A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival.0
250068032014Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer.0

Citation

Dessen P

SOX2-OT (SOX2 overlapping transcript)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54656/sox2-ot