SOX7 (SRY-box transcription factor 7)

2003-10-01  

Identity

HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 83595
MIM: 612202
HGNC: 18196
Ensembl: ENSG00000171056

Variants:

dbSNP: 83595
ClinVar: 83595
TCGA: ENSG00000171056
COSMIC: SOX7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171056ENST00000304501Q9BT81

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Deactivation of the beta-catenin transactivating complexREACTOMER-HSA-3769402

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385830212024[Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation].0
385830212024[Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation].0
367152132023The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner.5
367152132023The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner.5
352609392022Predisposition to atrioventricular septal defects may be caused by SOX7 variants that impair interaction with GATA4.1
356451022022SOX7 modulates the progression of hepatoblastoma through the regulation of Wnt/β-catenin signaling pathway.1
357181882022The mechanism by which crocetin regulates the lncRNA NEAT1/miR-125b-5p/SOX7 molecular axis to inhibit high glucose-induced diabetic retinopathy.4
352609392022Predisposition to atrioventricular septal defects may be caused by SOX7 variants that impair interaction with GATA4.1
356451022022SOX7 modulates the progression of hepatoblastoma through the regulation of Wnt/β-catenin signaling pathway.1
357181882022The mechanism by which crocetin regulates the lncRNA NEAT1/miR-125b-5p/SOX7 molecular axis to inhibit high glucose-induced diabetic retinopathy.4
337335172021SOX7 blocks vasculogenic mimicry in oral squamous cell carcinoma.2
338353992021CircUBQLN1 Promotes Proliferation but Inhibits Apoptosis and Oxidative Stress of Hippocampal Neurons in Epilepsy via the miR-155-Mediated SOX7 Upregulation.5
338462902021The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling.6
345702282021A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.5
347286262021Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization.32

Citation

Dessen P

SOX7 (SRY-box transcription factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/42359/sox7