Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30812
MIM: 605923
HGNC: 11203
Ensembl: ENSG00000005513
Variants:
dbSNP: 30812
ClinVar: 30812
TCGA: ENSG00000005513
COSMIC: SOX8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000005513 | ENST00000293894 | P57073 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36631813 | 2023 | Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development. | 2 |
| 36631813 | 2023 | Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development. | 2 |
| 35195773 | 2022 | SOX8 promotes cetuximab resistance via HGF/MET bypass pathway activation in colorectal cancer. | 3 |
| 36246971 | 2022 | SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway. | 2 |
| 35195773 | 2022 | SOX8 promotes cetuximab resistance via HGF/MET bypass pathway activation in colorectal cancer. | 3 |
| 36246971 | 2022 | SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway. | 2 |
| 34373588 | 2021 | Activation of RSK2 upregulates SOX8 to promote methotrexate resistance in gestational trophoblastic neoplasia. | 3 |
| 34373588 | 2021 | Activation of RSK2 upregulates SOX8 to promote methotrexate resistance in gestational trophoblastic neoplasia. | 3 |
| 32048324 | 2020 | Variation analysis of SOX8 gene in Chinese men with non-obstructive azoospermia or oligozoospermia. | 1 |
| 32307911 | 2020 | High SOX8 expression promotes tumor growth and predicts poor prognosis through GOLPH3 signaling in tongue squamous cell carcinoma. | 9 |
| 32550913 | 2020 | Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells. | 54 |
| 32767319 | 2020 | Low expression of CircRNA HIPK3 promotes osteoarthritis chondrocyte apoptosis by serving as a sponge of miR-124 to regulate SOX8. | 17 |
| 33190587 | 2020 | The oncogenic role of SOX8 in endometrial carcinoma. | 3 |
| 32048324 | 2020 | Variation analysis of SOX8 gene in Chinese men with non-obstructive azoospermia or oligozoospermia. | 1 |
| 32307911 | 2020 | High SOX8 expression promotes tumor growth and predicts poor prognosis through GOLPH3 signaling in tongue squamous cell carcinoma. | 9 |
Citation
Dessen P
SOX8 (SRY-box transcription factor 8)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50907/sox8
