SPAG1 (sperm associated antigen 1)

2007-07-01  

Identity

HGNC
LOCATION
8q22.2
LOCUSID
ALIAS
CILD28,CT140,DNAAF13,HEL-S-268,HSD-3.8,SP75,TPIS
FUSION GENES

Other Information

Locus ID:

NCBI: 6674
MIM: 603395
HGNC: 11212
Ensembl: ENSG00000104450

Variants:

dbSNP: 6674
ClinVar: 6674
TCGA: ENSG00000104450
COSMIC: SPAG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104450ENST00000251809Q07617
ENSG00000104450ENST00000388798Q07617
ENSG00000104450ENST00000520508Q07617
ENSG00000104450ENST00000520643Q07617

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
240551122013Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms.52
169833432007Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells.7
163685462006A sperm component, HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit and activates extracellular signal-regulated kinases (ERK).4
311182662019Binding properties of the quaternary assembly protein SPAG1.2
128467982003Isolation and characterization of a human sperm antigen gene h-Sp-1.1

Citation

Dessen P

SPAG1 (sperm associated antigen 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47639/spag1