Identity
HGNC
LOCATION
8q22.2
LOCUSID
ALIAS
CILD28,CT140,DNAAF13,HEL-S-268,HSD-3.8,SP75,TPIS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6674
MIM: 603395
HGNC: 11212
Ensembl: ENSG00000104450
Variants:
dbSNP: 6674
ClinVar: 6674
TCGA: ENSG00000104450
COSMIC: SPAG1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104450 | ENST00000251809 | Q07617 |
| ENSG00000104450 | ENST00000388798 | Q07617 |
| ENSG00000104450 | ENST00000520508 | Q07617 |
| ENSG00000104450 | ENST00000520643 | Q07617 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35178554 | 2022 | The role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia. | 3 |
| 35227274 | 2022 | Comprehensive analysis of SPAG1 expression as a prognostic and predictive biomarker in acute myeloid leukemia by integrative bioinformatics and clinical validation. | 4 |
| 35951456 | 2022 | SPAG1 promotes the development of AML by activating the ERK/MAPK signaling pathway and affects the chemotherapy sensitivity of venetoclax. | 1 |
| 35178554 | 2022 | The role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia. | 3 |
| 35227274 | 2022 | Comprehensive analysis of SPAG1 expression as a prognostic and predictive biomarker in acute myeloid leukemia by integrative bioinformatics and clinical validation. | 4 |
| 35951456 | 2022 | SPAG1 promotes the development of AML by activating the ERK/MAPK signaling pathway and affects the chemotherapy sensitivity of venetoclax. | 1 |
| 33739091 | 2021 | Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties. | 4 |
| 33739091 | 2021 | Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties. | 4 |
| 32619574 | 2020 | Bioinformatics analysis of the genes involved in the extension of prostate cancer to adjacent lymph nodes by supervised and unsupervised machine learning methods: The role of SPAG1 and PLEKHF2. | 11 |
| 32619574 | 2020 | Bioinformatics analysis of the genes involved in the extension of prostate cancer to adjacent lymph nodes by supervised and unsupervised machine learning methods: The role of SPAG1 and PLEKHF2. | 11 |
| 31118266 | 2019 | Binding properties of the quaternary assembly protein SPAG1. | 6 |
| 31118266 | 2019 | Binding properties of the quaternary assembly protein SPAG1. | 6 |
| 24055112 | 2013 | Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms. | 74 |
| 24055112 | 2013 | Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms. | 74 |
| 16983343 | 2007 | Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells. | 15 |
Citation
Dessen P
SPAG1 (sperm associated antigen 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47639/spag1
