SPAG11B (sperm associated antigen 11B)

2016-10-01  

Identity

HGNC
SPAG11B
LOCATION
8p23.1
LOCUSID
10407
ALIAS
EDDM2B,EP2,EP2C,EP2D,HE2,HE2C,SPAG11,SPAG11A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10407
MIM: 606560
HGNC: 14534
Ensembl: ENSG00000164871

Variants:

dbSNP: 10407
ClinVar: 10407
TCGA: ENSG00000164871
COSMIC: SPAG11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164871ENST00000297498Q08648
ENSG00000164871ENST00000317900Q08648
ENSG00000164871ENST00000359758A0A0A0MRG4
ENSG00000164871ENST00000398462Q08648
ENSG00000164871ENST00000458665Q08648
ENSG00000164871ENST00000528168Q08648
ENSG00000164871ENST00000528767A0A0B4J218
ENSG00000164871ENST00000528943H0YF39

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
219339542011Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay.32
121933882002Novel antimicrobial peptide of human epididymal duct origin.12
112592522001Organization of the human gene encoding the epididymis-specific EP2 protein variants and its relationship to defensin genes.10
152291352004Differential expression and antibacterial activity of epididymis protein 2 isoforms in the male reproductive tract of human and rhesus monkey (Macaca mulatta).9
164110222006Antimicrobial actions of human and macaque sperm associated antigen (SPAG) 11 isoforms: influence of the N-terminal peptide.7
108194502000Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2.6
195357872009Novel partners of SPAG11B isoform D in the human male reproductive tract.4
146627842004Vasectomy influences expression of HE1 but not HE2 and HE5 genes in human epididymis.3
255737892007Aggressive systemic mastocytosis after germ cell tumor of the ovary: C-KIT mutation documentation in both disease states.1

Citation

Dessen P

SPAG11B (sperm associated antigen 11B)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55955/spag11b