Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
CT89,HLC-6,HLC4,HLC6,JIP-4,JIP4,JLP,PHET,PIG6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9043
MIM: 605430
HGNC: 14524
Ensembl: ENSG00000008294
Variants:
dbSNP: 9043
ClinVar: 9043
TCGA: ENSG00000008294
COSMIC: SPAG9
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Myogenesis | REACTOME | R-HSA-525793 |
| CDO in myogenesis | REACTOME | R-HSA-375170 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36780531 | 2023 | An HLA-G/SPAG9/STAT3 axis promotes brain metastases. | 2 |
| 36780531 | 2023 | An HLA-G/SPAG9/STAT3 axis promotes brain metastases. | 2 |
| 34380828 | 2022 | Significance of cancer testis-associated antigens (SPAG9 and FBXO39) in colon cancer. | 0 |
| 34380828 | 2022 | Significance of cancer testis-associated antigens (SPAG9 and FBXO39) in colon cancer. | 0 |
| 33788575 | 2021 | Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons. | 27 |
| 34319782 | 2021 | Phosphorylation of JIP4 at S730 Presents Antiviral Properties against Influenza A Virus Infection. | 2 |
| 33788575 | 2021 | Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons. | 27 |
| 34319782 | 2021 | Phosphorylation of JIP4 at S730 Presents Antiviral Properties against Influenza A Virus Infection. | 2 |
| 32503577 | 2020 | miR-874 inhibits gastric cancer cell proliferation by targeting SPAG9. | 3 |
| 32776977 | 2020 | Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway. | 10 |
| 32503577 | 2020 | miR-874 inhibits gastric cancer cell proliferation by targeting SPAG9. | 3 |
| 32776977 | 2020 | Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway. | 10 |
| 31485599 | 2019 | LncRNA NEAT1 enhances the resistance of anaplastic thyroid carcinoma cells to cisplatin by sponging miR‑9‑5p and regulating SPAG9 expression. | 21 |
| 31690808 | 2019 | Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif. | 18 |
| 31485599 | 2019 | LncRNA NEAT1 enhances the resistance of anaplastic thyroid carcinoma cells to cisplatin by sponging miR‑9‑5p and regulating SPAG9 expression. | 21 |
Citation
Dessen P
SPAG9 (sperm associated antigen 9)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43500/spag9
