Identity
HGNC
LOCATION
15q14
LOCUSID
ALIAS
LGSS,NFLS,PPP1R147,hSpred1,spred-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 161742
MIM: 609291
HGNC: 20249
Ensembl: ENSG00000166068
Variants:
dbSNP: 161742
ClinVar: 161742
TCGA: ENSG00000166068
COSMIC: SPRED1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166068 | ENST00000299084 | Q7Z699 |
| ENSG00000166068 | ENST00000561317 | H0YMN8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36629984 | 2023 | SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo. | 2 |
| 37434064 | 2023 | Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/SPRED1 axis. | 0 |
| 36629984 | 2023 | SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo. | 2 |
| 37434064 | 2023 | Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/SPRED1 axis. | 0 |
| 33078527 | 2021 | Moyamoya syndrome in a child with Legius syndrome: Introducing a cerebral vasculopathy to the SPRED1 phenotype? | 1 |
| 33306107 | 2021 | SPRED1 deletion confers resistance to MAPK inhibition in melanoma. | 11 |
| 33078527 | 2021 | Moyamoya syndrome in a child with Legius syndrome: Introducing a cerebral vasculopathy to the SPRED1 phenotype? | 1 |
| 33306107 | 2021 | SPRED1 deletion confers resistance to MAPK inhibition in melanoma. | 11 |
| 32575496 | 2020 | Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected NF1 Patients. | 3 |
| 32773772 | 2020 | Constitutional mismatch repair deficiency is the diagnosis in 0.41% of pathogenic NF1/SPRED1 variant negative children suspected of sporadic neurofibromatosis type 1. | 4 |
| 33073945 | 2020 | A Study on the Expression of SPRED1 and PBRM1 (Baf180) and their Clinical Significances in Patients with Gastric Cancer. | 2 |
| 32575496 | 2020 | Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected NF1 Patients. | 3 |
| 32773772 | 2020 | Constitutional mismatch repair deficiency is the diagnosis in 0.41% of pathogenic NF1/SPRED1 variant negative children suspected of sporadic neurofibromatosis type 1. | 4 |
| 33073945 | 2020 | A Study on the Expression of SPRED1 and PBRM1 (Baf180) and their Clinical Significances in Patients with Gastric Cancer. | 2 |
| 30745814 | 2019 | A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia. | 6 |
Citation
Dessen P
SPRED1 (sprouty related EVH1 domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46102/spred1
