Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 200734
MIM: 609292
HGNC: 17722
Ensembl: ENSG00000198369
Variants:
dbSNP: 200734
ClinVar: 200734
TCGA: ENSG00000198369
COSMIC: SPRED2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38892460 | 2024 | SPRED2 Is a Novel Regulator of Autophagy in Hepatocellular Carcinoma Cells and Normal Hepatocytes. | 0 |
| 38892460 | 2024 | SPRED2 Is a Novel Regulator of Autophagy in Hepatocellular Carcinoma Cells and Normal Hepatocytes. | 0 |
| 36608738 | 2023 | Autosomal recessive Noonan-like syndrome caused by homozygosity for a previously unreported variant in SPRED2. | 1 |
| 36902429 | 2023 | SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells. | 5 |
| 37058811 | 2023 | SPRED2 promotes autophagy and attenuates inflammatory response in IL-1β induced osteoarthritis chondrocytes via regulating the p38 MAPK signaling pathway. | 2 |
| 37149146 | 2023 | The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling. | 3 |
| 36608738 | 2023 | Autosomal recessive Noonan-like syndrome caused by homozygosity for a previously unreported variant in SPRED2. | 1 |
| 36902429 | 2023 | SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells. | 5 |
| 37058811 | 2023 | SPRED2 promotes autophagy and attenuates inflammatory response in IL-1β induced osteoarthritis chondrocytes via regulating the p38 MAPK signaling pathway. | 2 |
| 37149146 | 2023 | The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling. | 3 |
| 34626534 | 2021 | SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype. | 21 |
| 34626534 | 2021 | SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype. | 21 |
| 32319644 | 2020 | Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling. | 7 |
| 33023313 | 2020 | miR-19 Promotes Cell Proliferation, Invasion, Migration, and EMT by Inhibiting SPRED2-mediated Autophagy in Osteosarcoma Cells. | 14 |
| 32319644 | 2020 | Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling. | 7 |
Citation
Dessen P
SPRED2 (sprouty related EVH1 domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45535/spred2
