SPRR2B (small proline rich protein 2B)

2012-04-01 Affiliation

Identity

HGNC

SPRR2B

LOCATION

1q21.3

LOCUSID

6701

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6701
MIM: 182268
HGNC: 11262
Ensembl: ENSG00000196805

Variants:

dbSNP: 6701
ClinVar: 6701
TCGA: ENSG00000196805
COSMIC: SPRR2B

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196805	ENST00000368755	P35325

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Developmental Biology	REACTOME	R-HSA-1266738
Keratinization	REACTOME	R-HSA-6805567
Formation of the cornified envelope	REACTOME	R-HSA-6809371

References

Pubmed ID	Year	Title	Citations
18643845	2009	Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.	16
22374195	2012	Genetic variation in small proline rich protein 2B as a predictor for asthma among children with eczema.	6
14748073	2004	Infection with Human Papillomavirus alters expression of the small proline rich proteins 2 and 3.	5
29581288	2018	Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.	5
21985131	2012	Four-gene expression model predictive of lymph node metastases in oral squamous cell carcinoma.	1

Citation

Dessen P

SPRR2B (small proline rich protein 2B)

Atlas Genet Cytogenet Oncol Haematol. 2012-04-01

Online version: http://atlasgeneticsoncology.org/gene/52667/sprr2b