SPRY3 (sprouty RTK signaling antagonist 3)

2014-11-01 Affiliation

Identity

HGNC

SPRY3

LOCATION

Xq28

LOCUSID

10251

ALIAS

spry-3

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10251
MIM: 300531
HGNC: 11271
Ensembl: ENSG00000168939

Variants:

dbSNP: 10251
ClinVar: 10251
TCGA: ENSG00000168939
COSMIC: SPRY3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000168939	ENST00000302805	O43610

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
15950061	2005	Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching.	21
16877379	2006	A functional interaction between sprouty proteins and caveolin-1.	11
26089202	2015	Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.	4
31374860	2019	Sprouty3 and Sprouty4, Two Members of a Family Known to Inhibit FGF-Mediated Signaling, Exert Opposing Roles on Proliferation and Migration of Glioblastoma-Derived Cells.	2

Citation

Dessen P

SPRY3 (sprouty RTK signaling antagonist 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74210/spry3