Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6713
MIM: 602019
HGNC: 11279
Ensembl: ENSG00000104549
Variants:
dbSNP: 6713
ClinVar: 6713
TCGA: ENSG00000104549
COSMIC: SQLE
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104549 | ENST00000265896 | Q14534 |
| ENSG00000104549 | ENST00000518931 | H0YBN7 |
| ENSG00000104549 | ENST00000521232 | E5RJH9 |
| ENSG00000104549 | ENST00000523430 | E7EVQ6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37993027 | 2024 | Knockdown of SQLE promotes CD8+ T cell infiltration in the tumor microenvironment. | 0 |
| 38280406 | 2024 | Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA. | 0 |
| 38372422 | 2024 | Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index. | 0 |
| 38612682 | 2024 | Squalene Epoxidase: Its Regulations and Links with Cancers. | 0 |
| 37993027 | 2024 | Knockdown of SQLE promotes CD8+ T cell infiltration in the tumor microenvironment. | 0 |
| 38280406 | 2024 | Squalene monooxygenase facilitates bladder cancer development in part by regulating PCNA. | 0 |
| 38372422 | 2024 | Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index. | 0 |
| 38612682 | 2024 | Squalene Epoxidase: Its Regulations and Links with Cancers. | 0 |
| 36581319 | 2023 | Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling. | 12 |
| 36843235 | 2023 | Squalene epoxidase facilitates cervical cancer progression by modulating tumor protein p53 signaling pathway. | 0 |
| 37139949 | 2023 | Report of terbinafine resistant Trichophyton spp. in Italy: Clinical presentations, molecular identification, antifungal susceptibility testing and mutations in the squalene epoxidase gene. | 6 |
| 37236595 | 2023 | Detection of Squalene Epoxidase Mutations in United States Patients with Onychomycosis: Implications for Management. | 8 |
| 37542052 | 2023 | SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway. | 9 |
| 37839786 | 2023 | Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability. | 1 |
| 38084535 | 2023 | The expression of squalene epoxidase in human gastric cancer and its clinical significance. | 0 |
Citation
Dessen P
SQLE (squalene epoxidase)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47598/sqle
