Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
DOMO1,EAF1,FLHS,SWR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10847
MIM: 611421
HGNC: 16974
Ensembl: ENSG00000080603
Variants:
dbSNP: 10847
ClinVar: 10847
TCGA: ENSG00000080603
COSMIC: SRCAP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000080603 | ENST00000262518 | Q6ZRS2 |
| ENSG00000080603 | ENST00000395059 | A0A0A0MS59 |
| ENSG00000080603 | ENST00000411466 | C9J4U4 |
| ENSG00000080603 | ENST00000483083 | A0A087X0E3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37863054 | 2023 | SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation. | 4 |
| 37863054 | 2023 | SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation. | 4 |
| 35152838 | 2022 | LINC00665 sponges miR-641 to promote the progression of breast cancer by targeting the SNF2-related CREBBP activator protein (SRCAP). | 2 |
| 35152838 | 2022 | LINC00665 sponges miR-641 to promote the progression of breast cancer by targeting the SNF2-related CREBBP activator protein (SRCAP). | 2 |
| 33307343 | 2021 | Cancer-related SRCAP and TPR mutations in colon cancers. | 6 |
| 33909990 | 2021 | Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature. | 26 |
| 34145229 | 2021 | Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder. | 7 |
| 33307343 | 2021 | Cancer-related SRCAP and TPR mutations in colon cancers. | 6 |
| 33909990 | 2021 | Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature. | 26 |
| 34145229 | 2021 | Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder. | 7 |
| 30337683 | 2018 | Cryo-EM structure of human SRCAP complex. | 15 |
| 30337683 | 2018 | Cryo-EM structure of human SRCAP complex. | 15 |
| 29138493 | 2017 | Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2. | 15 |
| 29138493 | 2017 | Suppression of SRCAP chromatin remodelling complex and restriction of lymphoid lineage commitment by Pcid2. | 15 |
| 27208210 | 2016 | When chromatin organisation floats astray: the Srcap gene and Floating-Harbor syndrome. | 16 |
Citation
Dessen P
SRCAP (Snf2 related CREBBP activator protein)
Atlas Genet Cytogenet Oncol Haematol. 2005-11-01
Online version: http://atlasgeneticsoncology.org/gene/43068/srcap
