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SRCIN1 (SRC kinase signaling inhibitor 1)

Identity

Other namesP140
SNIP
HGNC (Hugo) SRCIN1
LocusID (NCBI) 80725
Atlas_Id 49749
Location 17q12
Location_base_pair Starts at 36686259 and ends at 36762183 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SRCIN1   29506
Cards
Entrez_Gene (NCBI)SRCIN1  80725  SRC kinase signaling inhibitor 1
GeneCards (Weizmann)SRCIN1
Ensembl hg19 (Hinxton)ENSG00000277363 [Gene_View]  chr17:36686259-36762183 [Contig_View]  SRCIN1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000277363 [Gene_View]  chr17:36686259-36762183 [Contig_View]  SRCIN1 [Vega]
ICGC DataPortalENSG00000277363
TCGA cBioPortalSRCIN1
AceView (NCBI)SRCIN1
Genatlas (Paris)SRCIN1
WikiGenes80725
SOURCE (Princeton)SRCIN1
Genomic and cartography
GoldenPath hg19 (UCSC)SRCIN1  -     chr17:36686259-36762183 -  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SRCIN1  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblSRCIN1 - 17q12 [CytoView hg19]  SRCIN1 - 17q12 [CytoView hg38]
Mapping of homologs : NCBISRCIN1 [Mapview hg19]  SRCIN1 [Mapview hg38]
OMIM610786   
Gene and transcription
Genbank (Entrez)AB051471 AB127405 AK096097 AK126665 AK126676
RefSeq transcript (Entrez)NM_025248
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NT_187614 NW_004929407
Consensus coding sequences : CCDS (NCBI)SRCIN1
Cluster EST : UnigeneHs.448872 [ NCBI ]
CGAP (NCI)Hs.448872
Alternative Splicing : Fast-db (Paris)GSHG0013315
Alternative Splicing GalleryENSG00000277363
Gene ExpressionSRCIN1 [ NCBI-GEO ]     SRCIN1 [ SEEK ]   SRCIN1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0H9 (Uniprot)
NextProtQ9C0H9  [Medical]
With graphics : InterProQ9C0H9
Splice isoforms : SwissVarQ9C0H9 (Swissvar)
Domains : Interpro (EBI)Srcin1   
Related proteins : CluSTrQ9C0H9
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations80725
Blocks (Seattle)Q9C0H9
Human Protein AtlasENSG00000277363
Peptide AtlasQ9C0H9
HPRD11589
IPIIPI00479643   IPI00964306   IPI00384305   IPI00396130   IPI01013588   IPI00883713   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0H9
IntAct (EBI)Q9C0H9
FunCoupENSG00000277363
BioGRIDSRCIN1
IntegromeDBSRCIN1
STRING (EMBL)SRCIN1
Ontologies - Pathways
QuickGOQ9C0H9
Ontology : AmiGOprotein binding  cytoplasm  focal adhesion  exocytosis  postsynaptic density  actin cytoskeleton  protein kinase binding  regulation of cell migration  axon  dendrite  substrate adhesion-dependent cell spreading  synapse  postsynaptic membrane  regulation of dendritic spine morphogenesis  positive regulation of protein tyrosine kinase activity  negative regulation of protein tyrosine kinase activity  
Ontology : EGO-EBIprotein binding  cytoplasm  focal adhesion  exocytosis  postsynaptic density  actin cytoskeleton  protein kinase binding  regulation of cell migration  axon  dendrite  substrate adhesion-dependent cell spreading  synapse  postsynaptic membrane  regulation of dendritic spine morphogenesis  positive regulation of protein tyrosine kinase activity  negative regulation of protein tyrosine kinase activity  
Protein Interaction DatabaseSRCIN1
DoCM (Curated mutations)SRCIN1
Wikipedia pathwaysSRCIN1
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerSRCIN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SRCIN1
dbVarSRCIN1
ClinVarSRCIN1
1000_GenomesSRCIN1 
Exome Variant ServerSRCIN1
SNP (GeneSNP Utah)SRCIN1
SNP : HGBaseSRCIN1
Genetic variants : HAPMAPSRCIN1
Genomic Variants (DGV)SRCIN1 [DGVbeta]
Mutations
ICGC Data PortalSRCIN1 
TCGA Data PortalSRCIN1 
Tumor PortalSRCIN1
Somatic Mutations in Cancer : COSMICSRCIN1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:36686259-36762183
CONAN: Copy Number AnalysisSRCIN1 
Mutations and Diseases : HGMDSRCIN1
OMIM610786   
MedgenSRCIN1
NextProtQ9C0H9 [Medical]
GENETestsSRCIN1
Disease Genetic AssociationSRCIN1
Huge Navigator SRCIN1 [HugePedia]  SRCIN1 [HugeCancerGEM]
snp3D : Map Gene to Disease80725
DGIdb (Drug Gene Interaction db)SRCIN1
General knowledge
Homologs : HomoloGeneSRCIN1
Homology/Alignments : Family Browser (UCSC)SRCIN1
Phylogenetic Trees/Animal Genes : TreeFamSRCIN1
Chemical/Protein Interactions : CTD80725
Chemical/Pharm GKB GenePA165432823
Clinical trialSRCIN1
Cancer Resource (Charite)ENSG00000277363
Other databases
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
CoreMineSRCIN1
GoPubMedSRCIN1
iHOPSRCIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 15:17:44 CEST 2015

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