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SRCIN1 (SRC kinase signaling inhibitor 1)

Identity

Other namesP140
SNIP
HGNC (Hugo) SRCIN1
LocusID (NCBI) 80725
Location 17q12
Location_base_pair Starts at 36686259 and ends at 36762183 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)SRCIN1   29506
Cards
Entrez_Gene (NCBI)SRCIN1  80725  SRC kinase signaling inhibitor 1
GeneCards (Weizmann)SRCIN1
Ensembl (Hinxton)ENSG00000017373 [Gene_View]  chr17:36686259-36762183 [Contig_View]  SRCIN1 [Vega]
ICGC DataPortalENSG00000017373
cBioPortalSRCIN1
AceView (NCBI)SRCIN1
Genatlas (Paris)SRCIN1
WikiGenes80725
SOURCE (Princeton)NM_025248
Genomic and cartography
GoldenPath (UCSC)SRCIN1  -  17q12   chr17:36686259-36762183 -  17q12   [Description]    (hg19-Feb_2009)
EnsemblSRCIN1 - 17q12 [CytoView]
Mapping of homologs : NCBISRCIN1 [Mapview]
OMIM610786   
Gene and transcription
Genbank (Entrez)AB051471 AB127405 AK096097 AK126665 AK126676
RefSeq transcript (Entrez)NM_025248
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838435 NW_003315948 NW_004929407
Consensus coding sequences : CCDS (NCBI)SRCIN1
Cluster EST : UnigeneHs.448872 [ NCBI ]
CGAP (NCI)Hs.448872
Alternative Splicing : Fast-db (Paris)GSHG0013315
Alternative Splicing GalleryENSG00000017373
Gene ExpressionSRCIN1 [ NCBI-GEO ]     SRCIN1 [ SEEK ]   SRCIN1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0H9 (Uniprot)
NextProtQ9C0H9  [Medical]
With graphics : InterProQ9C0H9
Splice isoforms : SwissVarQ9C0H9 (Swissvar)
Domains : Interpro (EBI)Srcin1 [organisation]  
Related proteins : CluSTrQ9C0H9
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations80725
Blocks (Seattle)Q9C0H9
Human Protein AtlasENSG00000017373 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9C0H9
HPRD11589
IPIIPI00479643   IPI00964306   IPI00384305   IPI00396130   IPI01013588   IPI00883713   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0H9
IntAct (EBI)Q9C0H9
FunCoupENSG00000017373
BioGRIDSRCIN1
InParanoidQ9C0H9
Interologous Interaction database Q9C0H9
IntegromeDBSRCIN1
STRING (EMBL)SRCIN1
Ontologies - Pathways
Ontology : AmiGOprotein binding  cytoplasm  focal adhesion  exocytosis  negative regulation of cell adhesion  postsynaptic density  actin cytoskeleton  protein kinase binding  protein domain specific binding  lamellipodium  filopodium  regulation of cell migration  axon  dendrite  substrate adhesion-dependent cell spreading  neuronal cell body  synapse  postsynaptic membrane  negative regulation of protein secretion  regulation of dendritic spine morphogenesis  positive regulation of protein tyrosine kinase activity  negative regulation of protein tyrosine kinase activity  
Ontology : EGO-EBIprotein binding  cytoplasm  focal adhesion  exocytosis  negative regulation of cell adhesion  postsynaptic density  actin cytoskeleton  protein kinase binding  protein domain specific binding  lamellipodium  filopodium  regulation of cell migration  axon  dendrite  substrate adhesion-dependent cell spreading  neuronal cell body  synapse  postsynaptic membrane  negative regulation of protein secretion  regulation of dendritic spine morphogenesis  positive regulation of protein tyrosine kinase activity  negative regulation of protein tyrosine kinase activity  
Protein Interaction DatabaseSRCIN1
Wikipedia pathwaysSRCIN1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SRCIN1
snp3D : Map Gene to Disease80725
SNP (GeneSNP Utah)SRCIN1
SNP : HGBaseSRCIN1
Genetic variants : HAPMAPSRCIN1
Exome VariantSRCIN1
1000_GenomesSRCIN1 
ICGC programENSG00000017373 
Somatic Mutations in Cancer : COSMICSRCIN1 
CONAN: Copy Number AnalysisSRCIN1 
Mutations and Diseases : HGMDSRCIN1
Genomic VariantsSRCIN1  SRCIN1 [DGVbeta]
dbVarSRCIN1
ClinVarSRCIN1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM610786   
MedgenSRCIN1
GENETestsSRCIN1
Disease Genetic AssociationSRCIN1
Huge Navigator SRCIN1 [HugePedia]  SRCIN1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSRCIN1
Homology/Alignments : Family Browser (UCSC)SRCIN1
Phylogenetic Trees/Animal Genes : TreeFamSRCIN1
Chemical/Protein Interactions : CTD80725
Chemical/Pharm GKB GenePA165432823
Clinical trialSRCIN1
Cancer Resource (Charite)ENSG00000017373
Other databases
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
CoreMineSRCIN1
iHOPSRCIN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 17:20:54 CEST 2014

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