SSR3 (signal sequence receptor subunit 3)

2003-06-01  

Identity

HGNC
SSR3
LOCATION
3q25.31
LOCUSID
6747
ALIAS
TRAPG
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6747
MIM: 606213
HGNC: 11325
Ensembl: ENSG00000114850

Variants:

dbSNP: 6747
ClinVar: 6747
TCGA: ENSG00000114850
COSMIC: SSR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114850ENST00000265044Q9UNL2
ENSG00000114850ENST00000463503C9J365
ENSG00000114850ENST00000467789Q9UNL2
ENSG00000114850ENST00000476217C9JA28
ENSG00000114850ENST00000496050C9J365

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Translocon-associated protein (TRAP) complexKEGGhsa_M00402
Translocon-associated protein (TRAP) complexKEGGM00402
Metabolism of proteinsREACTOMER-HSA-392499
TranslationREACTOMER-HSA-72766
SRP-dependent cotranslational protein targeting to membraneREACTOMER-HSA-1799339
Gene ExpressionREACTOMER-HSA-74160

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
282182522017Dissecting the molecular organization of the translocon-associated protein complex.27
236602952013The orphan nuclear receptor TR3/Nur77 regulates ER stress and induces apoptosis via interaction with TRAPγ.7
299402862018Overexpression of signal sequence receptor γ predicts poor survival in patients with hepatocellular carcinoma.2

Citation

Dessen P

SSR3 (signal sequence receptor subunit 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42399/ssr3