Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55620
MIM: 607881
HGNC: 30430
Ensembl: ENSG00000178078
Variants:
dbSNP: 55620
ClinVar: 55620
TCGA: ENSG00000178078
COSMIC: STAP2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by PTK6 | REACTOME | R-HSA-8848021 |
| PTK6 Activates STAT3 | REACTOME | R-HSA-8849474 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38461189 | 2024 | STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation. | 0 |
| 38461189 | 2024 | STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation. | 0 |
| 34780812 | 2022 | Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases. | 1 |
| 34780812 | 2022 | Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases. | 1 |
| 28430604 | 2017 | Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation. | 5 |
| 28478037 | 2017 | STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells. | 2 |
| 28986450 | 2017 | STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization. | 12 |
| 28430604 | 2017 | Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation. | 5 |
| 28478037 | 2017 | STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells. | 2 |
| 28986450 | 2017 | STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization. | 12 |
| 23700042 | 2013 | Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse. | 6 |
| 23700042 | 2013 | Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse. | 6 |
| 22231445 | 2012 | STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis. | 11 |
| 22611243 | 2012 | Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8. | 7 |
| 22231445 | 2012 | STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis. | 11 |
Citation
Dessen P
STAP2 (signal transducing adaptor family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-02-01
Online version: http://atlasgeneticsoncology.org/gene/52081/stap2
