STH (saitohin)

2014-11-01 Affiliation

Identity

HGNC

STH

LOCATION

17q21.31

LOCUSID

246744

ALIAS

MAPTIT

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 246744
MIM: 607067
HGNC: 18839
Ensembl: ENSG00000256762

Variants:

dbSNP: 246744
ClinVar: 246744
TCGA: ENSG00000256762
COSMIC: STH

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000256762	ENST00000537309	Q8IWL8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
18509094	2008	Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study.	34
12032355	2002	A polymorphic gene nested within an intron of the tau gene: implications for Alzheimer's disease.	21
16603077	2006	Variation at APOE and STH loci and Alzheimer's disease.	15
16909000	2005	TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.	10
16909000	2005	TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.	10
16186110	2005	Saitohin, which is nested in the tau locus and confers allele-specific susceptibility to several neurodegenerative diseases, interacts with peroxiredoxin 6.	9
18307033	2009	Cluster analysis of risk factor genetic polymorphisms in Alzheimer's disease.	7
12826737	2003	Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia.	5
12932819	2003	Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population.	5
18396294	2008	Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease.	5

Citation

Dessen P

STH (saitohin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74307/sth