STK16 (serine/threonine kinase 16)

2006-10-01  

Identity

HGNC
STK16
LOCATION
2q35
LOCUSID
8576
ALIAS
KRCT,MPSK,PKL12,PSK,TSF1,hPSK
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8576
MIM: 604719
HGNC: 11394
Ensembl: ENSG00000115661

Variants:

dbSNP: 8576
ClinVar: 8576
TCGA: ENSG00000115661
COSMIC: STK16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115661ENST00000396738O75716
ENSG00000115661ENST00000396738A0A024R440
ENSG00000115661ENST00000409260B8ZZN3
ENSG00000115661ENST00000409516B4DPS1
ENSG00000115661ENST00000409638O75716
ENSG00000115661ENST00000409638A0A024R440
ENSG00000115661ENST00000409743B8ZZI5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386225182024STK16 promoted colorectal cancer progress in a c-MYC signaling-dependent manner.0
387237202024Serine/Threonine kinase 16 phosphorylates STAT3 and confers a JAK2-Inhibition resistance phenotype in triple-negative breast cancer.0
386225182024STK16 promoted colorectal cancer progress in a c-MYC signaling-dependent manner.0
387237202024Serine/Threonine kinase 16 phosphorylates STAT3 and confers a JAK2-Inhibition resistance phenotype in triple-negative breast cancer.0
350921212022Exosomes from M1-polarized macrophages promote apoptosis in lung adenocarcinoma via the miR-181a-5p/ETS1/STK16 axis.15
350921212022Exosomes from M1-polarized macrophages promote apoptosis in lung adenocarcinoma via the miR-181a-5p/ETS1/STK16 axis.15
282941562017STK16 regulates actin dynamics to control Golgi organization and cell cycle.12
282941562017STK16 regulates actin dynamics to control Golgi organization and cell cycle.12
250845252014Serine/threonine kinase 16 and MAL2 regulate constitutive secretion of soluble cargo in hepatic cells.18
250845252014Serine/threonine kinase 16 and MAL2 regulate constitutive secretion of soluble cargo in hepatic cells.18
163107702006Nucleocytoplasmic shuttling of STK16 (PKL12), a Golgi-resident serine/threonine kinase involved in VEGF expression regulation.14
163107702006Nucleocytoplasmic shuttling of STK16 (PKL12), a Golgi-resident serine/threonine kinase involved in VEGF expression regulation.14

Citation

Dessen P

STK16 (serine/threonine kinase 16)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43507/stk16