Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6788
MIM: 605030
HGNC: 11406
Ensembl: ENSG00000104375
Variants:
dbSNP: 6788
ClinVar: 6788
TCGA: ENSG00000104375
COSMIC: STK3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38443598 | 2024 | The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress. | 1 |
| 38443598 | 2024 | The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress. | 1 |
| 36495715 | 2023 | Mammalian STE20-like kinase-1/2 are activated in human platelets stimulated by collagen or thrombin and play a vital role in collagen-activated platelets. | 0 |
| 37354905 | 2023 | TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2. | 3 |
| 37739411 | 2023 | The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation. | 0 |
| 37890777 | 2023 | Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions. | 0 |
| 37905571 | 2023 | MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression. | 3 |
| 36495715 | 2023 | Mammalian STE20-like kinase-1/2 are activated in human platelets stimulated by collagen or thrombin and play a vital role in collagen-activated platelets. | 0 |
| 37354905 | 2023 | TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2. | 3 |
| 37739411 | 2023 | The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation. | 0 |
| 37890777 | 2023 | Smurf1 polyubiquitinates on K285/K282 of the kinases Mst1/2 to attenuate their tumor-suppressor functions. | 0 |
| 37905571 | 2023 | MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression. | 3 |
| 34450249 | 2022 | Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer. | 9 |
| 35253468 | 2022 | MST1/2 in PDGFRα(+) cells negatively regulates TGF-β-induced myofibroblast accumulation in renal fibrosis. | 3 |
| 35452623 | 2022 | High MST2 expression regulates lens epithelial cell apoptosis in age-related cataracts through YAP1 targeting GLUT1. | 2 |
Citation
Dessen P
STK3 (serine/threonine kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42439/stk3
