Identity
HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
MAWD,PT-WD,UNRIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11171
MIM: 605986
HGNC: 30796
Ensembl: ENSG00000023734
Variants:
dbSNP: 11171
ClinVar: 11171
TCGA: ENSG00000023734
COSMIC: STRAP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000023734 | ENST00000025399 | Q9Y3F4 |
| ENSG00000023734 | ENST00000419869 | Q9Y3F4 |
| ENSG00000023734 | ENST00000538718 | H0YH33 |
| ENSG00000023734 | ENST00000541731 | F5H1G1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34520730 | 2022 | Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism. | 4 |
| 35272839 | 2022 | Serine-Threonine Kinase Receptor Associate Protein (STRAP) confers an aggressive phenotype in neuroblastoma via regulation of Focal Adhesion Kinase (FAK). | 2 |
| 34520730 | 2022 | Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism. | 4 |
| 35272839 | 2022 | Serine-Threonine Kinase Receptor Associate Protein (STRAP) confers an aggressive phenotype in neuroblastoma via regulation of Focal Adhesion Kinase (FAK). | 2 |
| 32527012 | 2020 | SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability. | 8 |
| 32527012 | 2020 | SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability. | 8 |
| 30257989 | 2019 | Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling. | 8 |
| 30257989 | 2019 | Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/β-Catenin Signaling. | 8 |
| 29283497 | 2018 | Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level. | 6 |
| 29783958 | 2018 | Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK. | 21 |
| 30138317 | 2018 | Strap associates with Csde1 and affects expression of select Csde1-bound transcripts. | 5 |
| 29283497 | 2018 | Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level. | 6 |
| 29783958 | 2018 | Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK. | 21 |
| 30138317 | 2018 | Strap associates with Csde1 and affects expression of select Csde1-bound transcripts. | 5 |
| 28827371 | 2017 | STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. | 46 |
Citation
Dessen P
STRAP (serine/threonine kinase receptor associated protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42445/strap
