STYX (serine/threonine/tyrosine interacting protein)

2014-11-01  

Identity

HGNC
LOCATION
14q22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 6815
MIM: 615814
HGNC: 11447
Ensembl: ENSG00000198252

Variants:

dbSNP: 6815
ClinVar: 6815
TCGA: ENSG00000198252
COSMIC: STYX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198252ENST00000354586Q8WUJ0
ENSG00000198252ENST00000354586A0A024R641
ENSG00000198252ENST00000442123Q8WUJ0
ENSG00000198252ENST00000442123A0A024R641

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
238472092013Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.12
280078942017The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.8
193696472009Identification of potentially damaging amino acid substitutions leading to human male infertility.2
284084852017STYX: a versatile pseudophosphatase.2
309817572019Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer.2

Citation

Dessen P

STYX (serine/threonine/tyrosine interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74349/styx