SUGP1 (SURP and G-patch domain containing 1)

2014-11-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
F23858,RBP,SF4
FUSION GENES

Other Information

Locus ID:

NCBI: 57794
MIM: 607992
HGNC: 18643
Ensembl: ENSG00000105705

Variants:

dbSNP: 57794
ClinVar: 57794
TCGA: ENSG00000105705
COSMIC: SUGP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105705ENST00000247001Q8IWZ8
ENSG00000105705ENST00000535070B4DVK3
ENSG00000105705ENST00000585444K7ESM0
ENSG00000105705ENST00000587119K7ELR6
ENSG00000105705ENST00000589144K7EM86
ENSG00000105705ENST00000590439V9GZ08
ENSG00000105705ENST00000591350K7ES12

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
196567732009A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.25
314745742019Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.7
272069822016SUGP1 is a novel regulator of cholesterol metabolism.5

Citation

Dessen P

SUGP1 (SURP and G-patch domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74359/sugp1