Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6817
MIM: 171150
HGNC: 11453
Ensembl: ENSG00000196502
Variants:
dbSNP: 6817
ClinVar: 6817
TCGA: ENSG00000196502
COSMIC: SULT1A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164754789 | conjugated estrogens | Chemical | ClinicalAnnotation | associated | PD | 16985250 | |
| PA165947774 | SULT1A1*2 | Haplotype | VipGene | associated | |||
| PA166154995 | rs750155 | Variant | VipGene | associated | 15970794 | ||
| PA166155019 | rs1801030 | Variant | VipGene | associated | 11207031, 10413297 | ||
| PA166155051 | rs3760091 | Variant | VipGene | associated | 15970794 | ||
| PA166155089 | rs9282861 | Variant | VipGene | associated | 10423517, 10959796, 11207031, 11535246, 14520706, 14973106, 15093672, 15377847, 15632378, 16141802, 18368507, 9345314, 10413297 | ||
| PA166163690 | desmethylnaproxen | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | ||
| PA166179720 | tapentadol | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | ||
| PA443560 | Breast Neoplasms | Disease | VipGene | associated | 15093672, 15377847, 16141802, 14520706 | ||
| PA444101 | Esophageal Neoplasms | Disease | VipGene | associated | 16272171 | ||
| PA445208 | Pain | Disease | ClinicalAnnotation | associated | PD | 30908574 | |
| PA445425 | Prostatic Neoplasms | Disease | VipGene | associated | 14973106, 10959796 | ||
| PA446108 | Colorectal Neoplasms | Disease | VipGene | associated | |||
| PA446411 | Endometrial Neoplasms | Disease | ClinicalAnnotation | associated | PD | 16985250 | |
| PA448015 | acetaminophen | Chemical | ClinicalAnnotation, Literature, MultilinkAnnotation, Pathway, VipGene | associated | PK | PD | 23462933, 26049587, 30908574, 6957279 |
| PA449509 | estrogens | Chemical | VipGene | associated | 11906176, 12034366, 9068609, 11062153 | ||
| PA450521 | minoxidil | Chemical | VipGene | associated | 2390100 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38069221 | 2023 | Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity. | 0 |
| 38069221 | 2023 | Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity. | 0 |
| 33297275 | 2021 | Investigating the molecular mechanism of hydroxylated bromdiphenyl ethers to inhibit the thyroid hormone sulfotransferase SULT1A1. | 2 |
| 34162941 | 2021 | Insights into the substrate binding mechanism of SULT1A1 through molecular dynamics with excited normal modes simulations. | 8 |
| 33297275 | 2021 | Investigating the molecular mechanism of hydroxylated bromdiphenyl ethers to inhibit the thyroid hormone sulfotransferase SULT1A1. | 2 |
| 34162941 | 2021 | Insights into the substrate binding mechanism of SULT1A1 through molecular dynamics with excited normal modes simulations. | 8 |
| 31671219 | 2020 | Prediagnostic circulating inflammation biomarkers and esophageal squamous cell carcinoma: A case-cohort study in Japan. | 15 |
| 32152050 | 2020 | Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function. | 6 |
| 33049293 | 2020 | Evaluation of a conserved tryptophanyl residue in donor substrate binding and catalysis by a phenol sulfotransferase (SULT1A1). | 0 |
| 31671219 | 2020 | Prediagnostic circulating inflammation biomarkers and esophageal squamous cell carcinoma: A case-cohort study in Japan. | 15 |
| 32152050 | 2020 | Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function. | 6 |
| 33049293 | 2020 | Evaluation of a conserved tryptophanyl residue in donor substrate binding and catalysis by a phenol sulfotransferase (SULT1A1). | 0 |
| 31835852 | 2019 | Structural and Dynamic Characterizations Highlight the Deleterious Role of SULT1A1 R213H Polymorphism in Substrate Binding. | 21 |
| 31835852 | 2019 | Structural and Dynamic Characterizations Highlight the Deleterious Role of SULT1A1 R213H Polymorphism in Substrate Binding. | 21 |
| 29790428 | 2018 | Multi-ethnic SULT1A1 copy number profiling with multiplex ligation-dependent probe amplification. | 7 |
Citation
Dessen P
SULT1A1 (sulfotransferase family 1A member 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42449/sult1a1
