SULT1A2 (sulfotransferase family 1A member 2)

2007-02-01  

Identity

HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
HAST4,P-PST,P-PST

Other Information

Locus ID:

NCBI: 6799
MIM: 601292
HGNC: 11454
Ensembl: ENSG00000197165

Variants:

dbSNP: 6799
ClinVar: 6799
TCGA: ENSG00000197165
COSMIC: SULT1A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197165ENST00000335715P50226
ENSG00000197165ENST00000395630P50226
ENSG00000197165ENST00000526384E9PKR8
ENSG00000197165ENST00000533150E9PKW4
ENSG00000197165ENST00000534108E9PM76

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Chemical carcinogenesisKEGGhsa05204
Chemical carcinogenesisKEGGko05204
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371427022023Association of SULT1A2 rs1059491 with obesity and dyslipidaemia in southern Chinese adults.0
371427022023Association of SULT1A2 rs1059491 with obesity and dyslipidaemia in southern Chinese adults.0
299083032018Hemoglobin adducts of furfuryl alcohol in genetically modified mouse models: Role of endogenous sulfotransferases 1a1 and 1d1 and transgenic human sulfotransferases 1A1/1A2.1
299083032018Hemoglobin adducts of furfuryl alcohol in genetically modified mouse models: Role of endogenous sulfotransferases 1a1 and 1d1 and transgenic human sulfotransferases 1A1/1A2.1
264558292016Genotypes of CYP1A1, SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India.4
264558292016Genotypes of CYP1A1, SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India.4
261695782015Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis.11
261695782015Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis.11
233582612013Single nucleotide polymorphisms in SULT1A1 and SULT1A2 in a Korean population.1
239229542013Relationship between genotypes Sult1a2 and Cyp2d6 and tamoxifen metabolism in breast cancer patients.21
233582612013Single nucleotide polymorphisms in SULT1A1 and SULT1A2 in a Korean population.1
239229542013Relationship between genotypes Sult1a2 and Cyp2d6 and tamoxifen metabolism in breast cancer patients.21
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.30
202148022010Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.11
204171802010Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.10

Citation

Dessen P

SULT1A2 (sulfotransferase family 1A member 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46197/sult1a2