SULT1A2 (sulfotransferase family 1A member 2)

2007-02-01  

Identity

HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
HAST4,P-PST,P-PST

Other Information

Locus ID:

NCBI: 6799
MIM: 601292
HGNC: 11454
Ensembl: ENSG00000197165

Variants:

dbSNP: 6799
ClinVar: 6799
TCGA: ENSG00000197165
COSMIC: SULT1A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197165ENST00000335715P50226
ENSG00000197165ENST00000395630P50226
ENSG00000197165ENST00000526384E9PKR8
ENSG00000197165ENST00000533150E9PKW4
ENSG00000197165ENST00000534108E9PM76

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Chemical carcinogenesisKEGGhsa05204
Chemical carcinogenesisKEGGko05204
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
124198322002A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.58
189921482008Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.32
186327532008Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.28
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
112070312001Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects.20
239229542013Relationship between genotypes Sult1a2 and Cyp2d6 and tamoxifen metabolism in breast cancer patients.14
202148022010Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.11
182596932009Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2).10
182596932009Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2).10
205297632010Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.8

Citation

Dessen P

SULT1A2 (sulfotransferase family 1A member 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46197/sult1a2