SULT1C4 (sulfotransferase family 1C member 4)

2014-11-01 Affiliation

Identity

HGNC

SULT1C4

LOCATION

2q12.3

LOCUSID

27233

ALIAS

SULT1C,SULT1C2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 27233
MIM: 608357
HGNC: 11457
Ensembl: ENSG00000198075

Variants:

dbSNP: 27233
ClinVar: 27233
TCGA: ENSG00000198075
COSMIC: SULT1C4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000198075	ENST00000272452	O75897
ENSG00000198075	ENST00000409309	O75897

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism	REACTOME	R-HSA-1430728
Biological oxidations	REACTOME	R-HSA-211859
Phase II conjugation	REACTOME	R-HSA-156580
Cytosolic sulfonation of small molecules	REACTOME	R-HSA-156584

PharmGKB

Entity ID	Name	Type	Evidence	Association	PD	PMIDs
PA445425	Prostatic Neoplasms	Disease	ClinicalAnnotation	associated	PD	20038957
PA449383	docetaxel	Chemical	ClinicalAnnotation	associated	PD	20038957
PA451644	thalidomide	Chemical	ClinicalAnnotation	associated	PD	20038957

References

Pubmed ID	Year	Title	Citations
26067475	2015	Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis.	8
26948952	2016	Human cytosolic sulfotransferase SULT1C4 mediates the sulfation of doxorubicin and epirubicin.	0

Citation

Dessen P

SULT1C4 (sulfotransferase family 1C member 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74368/sult1c4