Identity
HGNC
LOCATION
19q13.33
LOCUSID
ALIAS
ARCI14,HSST2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6820
MIM: 604125
HGNC: 11459
Ensembl: ENSG00000088002
Variants:
dbSNP: 6820
ClinVar: 6820
TCGA: ENSG00000088002
COSMIC: SULT2B1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000088002 | ENST00000201586 | O00204 |
| ENSG00000088002 | ENST00000323090 | O00204 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130620651 | anthracyclines and related substances | Chemical | ClinicalAnnotation | associated | PD | 21900104, 23441093 | |
| PA164749431 | gemtuzumab ozogamicin | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA444760 | Leukemia, Myeloid, Acute | Disease | ClinicalAnnotation | associated | PD | 22584460 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 21900104, 23441093 | |
| PA449177 | cytarabine | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA449655 | fludarabine | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA449961 | idarubicin | Chemical | ClinicalAnnotation | associated | PD | 22584460 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38286358 | 2024 | Reducing SULT2B1 promotes the interaction of LncRNAgga3-204 with SMAD4 to inhibit the macrophage inflammatory response and delay atherosclerosis progression. | 0 |
| 38372484 | 2024 | Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1-mediated lipid metabolism. | 0 |
| 38286358 | 2024 | Reducing SULT2B1 promotes the interaction of LncRNAgga3-204 with SMAD4 to inhibit the macrophage inflammatory response and delay atherosclerosis progression. | 0 |
| 38372484 | 2024 | Sulfotransferase SULT2B1 facilitates colon cancer metastasis by promoting SCD1-mediated lipid metabolism. | 0 |
| 37550000 | 2023 | Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration. | 1 |
| 37550000 | 2023 | Macrophage Sult2b1 promotes pathological neovascularization in age-related macular degeneration. | 1 |
| 34730281 | 2021 | The promoter hypermethylation of SULT2B1 accelerates esophagus tumorigenesis via downregulated PER1. | 6 |
| 34730281 | 2021 | The promoter hypermethylation of SULT2B1 accelerates esophagus tumorigenesis via downregulated PER1. | 6 |
| 31894239 | 2020 | Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer. | 5 |
| 31957803 | 2020 | SULT2B1b inhibits reverse cholesterol transport and promotes cholesterol accumulation and inflammation in lymphocytes from AMI patients with low LDL-C levels. | 4 |
| 31894239 | 2020 | Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer. | 5 |
| 31957803 | 2020 | SULT2B1b inhibits reverse cholesterol transport and promotes cholesterol accumulation and inflammation in lymphocytes from AMI patients with low LDL-C levels. | 4 |
| 30658852 | 2019 | SULT2B1b promotes epithelial-mesenchymal transition through activation of the β-catenin/MMP7 pathway in hepatocytes. | 15 |
| 30824526 | 2019 | Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNFα in Castration-Resistant Prostate Cancer. | 5 |
| 31212370 | 2019 | Distinct expression patterns of SULT2B1b in human prostate epithelium. | 3 |
Citation
Dessen P
SULT2B1 (sulfotransferase family 2B member 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-10-01
Online version: http://atlasgeneticsoncology.org/gene/50436/sult2b1
