Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SUSD6 (sushi domain containing 6)

Identity

Alias_namesKIAA0247
KIAA0247
Other aliasDRAGO
HGNC (Hugo) SUSD6
LocusID (NCBI) 9766
Atlas_Id 54965
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 69611593 and ends at 69715144 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BRK1 (3p25.3) / SUSD6 (14q24.1)EYA3 (1p35.3) / SUSD6 (14q24.1)HSPG2 (1p36.12) / SUSD6 (14q24.1)
LST1 (6p21.33) / SUSD6 (14q24.1)PHF1 (6p21.32) / SUSD6 (14q24.1)SUSD6 (14q24.1) / BRK1 (3p25.3)
SUSD6 (14q24.1) / FAM131B (7q34)SUSD6 (14q24.1) / PPP2R5E (14q23.2)SUSD6 (14q24.1) / RAD51B (14q24.1)
SUSD6 (14q24.1) / TXNDC16 (14q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(14;14)(q24;q24) SUSD6/RBM25

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(1;14)(p35;q24) EYA3/SUSD6
t(1;14)(p36;q24) HSPG2/SUSD6
t(14;14)(q22;q24) SUSD6/TXNDC16
SUSD6/RAD51B (14q24)

External links

Nomenclature
HGNC (Hugo)SUSD6   19956
Cards
Entrez_Gene (NCBI)SUSD6  9766  sushi domain containing 6
AliasesDRAGO; KIAA0247
GeneCards (Weizmann)SUSD6
Ensembl hg19 (Hinxton)ENSG00000100647 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100647 [Gene_View]  ENSG00000100647 [Sequence]  chr14:69611593-69715144 [Contig_View]  SUSD6 [Vega]
ICGC DataPortalENSG00000100647
TCGA cBioPortalSUSD6
AceView (NCBI)SUSD6
Genatlas (Paris)SUSD6
WikiGenes9766
SOURCE (Princeton)SUSD6
Genetics Home Reference (NIH)SUSD6
Genomic and cartography
GoldenPath hg38 (UCSC)SUSD6  -     chr14:69611593-69715144 +  14q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUSD6  -     14q24.1   [Description]    (hg19-Feb_2009)
GoldenPathSUSD6 - 14q24.1 [CytoView hg19]  SUSD6 - 14q24.1 [CytoView hg38]
ImmunoBaseENSG00000100647
Mapping of homologs : NCBISUSD6 [Mapview hg19]  SUSD6 [Mapview hg38]
OMIM616761   
Gene and transcription
Genbank (Entrez)AK130809 AK309302 AK311470 BC064697 D87434
RefSeq transcript (Entrez)NM_014734
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SUSD6
Cluster EST : UnigeneHs.440025 [ NCBI ]
CGAP (NCI)Hs.440025
Alternative Splicing GalleryENSG00000100647
Gene ExpressionSUSD6 [ NCBI-GEO ]   SUSD6 [ EBI - ARRAY_EXPRESS ]   SUSD6 [ SEEK ]   SUSD6 [ MEM ]
Gene Expression Viewer (FireBrowse)SUSD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9766
GTEX Portal (Tissue expression)SUSD6
Human Protein AtlasENSG00000100647-SUSD6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92537   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92537  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92537
Splice isoforms : SwissVarQ92537
PhosPhoSitePlusQ92537
Domaine pattern : Prosite (Expaxy)SUSHI (PS50923)   
Domains : Interpro (EBI)Sushi/SCR/CCP_sf    Sushi_SCR_CCP_dom   
Domain families : Pfam (Sanger)Sushi (PF00084)   
Domain families : Pfam (NCBI)pfam00084   
Domain families : Smart (EMBL)CCP (SM00032)  
Conserved Domain (NCBI)SUSD6
DMDM Disease mutations9766
Blocks (Seattle)SUSD6
SuperfamilyQ92537
Human Protein Atlas [tissue]ENSG00000100647-SUSD6 [tissue]
Peptide AtlasQ92537
HPRD10010
IPIIPI00021951   
Protein Interaction databases
DIP (DOE-UCLA)Q92537
IntAct (EBI)Q92537
FunCoupENSG00000100647
BioGRIDSUSD6
STRING (EMBL)SUSD6
ZODIACSUSD6
Ontologies - Pathways
QuickGOQ92537
Ontology : AmiGOmolecular_function  protein binding  cellular_component  cellular response to DNA damage stimulus  cell death  integral component of membrane  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  cellular response to DNA damage stimulus  cell death  integral component of membrane  
NDEx NetworkSUSD6
Atlas of Cancer Signalling NetworkSUSD6
Wikipedia pathwaysSUSD6
Orthology - Evolution
OrthoDB9766
GeneTree (enSembl)ENSG00000100647
Phylogenetic Trees/Animal Genes : TreeFamSUSD6
HOGENOMQ92537
Homologs : HomoloGeneSUSD6
Homology/Alignments : Family Browser (UCSC)SUSD6
Gene fusions - Rearrangements
Fusion : MitelmanEYA3/SUSD6 [1p35.3/14q24.1]  [t(1;14)(p35;q24)]  
Fusion : MitelmanHSPG2/SUSD6 [1p36.12/14q24.1]  [t(1;14)(p36;q24)]  
Fusion : MitelmanSUSD6/RAD51B [14q24.1/14q24.1]  [t(14;14)(q24;q24)]  
Fusion : MitelmanSUSD6/TXNDC16 [14q24.1/14q22.1]  [t(14;14)(q22;q24)]  
Fusion : QuiverSUSD6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUSD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUSD6
dbVarSUSD6
ClinVarSUSD6
1000_GenomesSUSD6 
Exome Variant ServerSUSD6
ExAC (Exome Aggregation Consortium)ENSG00000100647
GNOMAD BrowserENSG00000100647
Varsome BrowserSUSD6
Genetic variants : HAPMAP9766
Genomic Variants (DGV)SUSD6 [DGVbeta]
DECIPHERSUSD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUSD6 
Mutations
ICGC Data PortalSUSD6 
TCGA Data PortalSUSD6 
Broad Tumor PortalSUSD6
OASIS PortalSUSD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUSD6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSUSD6
Mutations and Diseases : HGMDSUSD6
BioMutasearch SUSD6
DgiDB (Drug Gene Interaction Database)SUSD6
DoCM (Curated mutations)SUSD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUSD6 (select a term)
intoGenSUSD6
Cancer3DSUSD6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616761   
Orphanet
DisGeNETSUSD6
MedgenSUSD6
Genetic Testing Registry SUSD6
NextProtQ92537 [Medical]
TSGene9766
GENETestsSUSD6
Target ValidationSUSD6
Huge Navigator SUSD6 [HugePedia]
snp3D : Map Gene to Disease9766
BioCentury BCIQSUSD6
ClinGenSUSD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9766
Chemical/Pharm GKB GenePA128394557
Clinical trialSUSD6
Miscellaneous
canSAR (ICR)SUSD6 (select the gene name)
DataMed IndexSUSD6
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUSD6
EVEXSUSD6
GoPubMedSUSD6
iHOPSUSD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:10:26 CET 2019
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