Identity
HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
CT8,HOM-TES-14,SCP-1,SCP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6847
MIM: 602162
HGNC: 11487
Ensembl: ENSG00000198765
Variants:
dbSNP: 6847
ClinVar: 6847
TCGA: ENSG00000198765
COSMIC: SYCP1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic synapsis | REACTOME | R-HSA-1221632 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35377450 | 2022 | A rare frameshift mutation in SYCP1 is associated with human male infertility. | 3 |
| 35377450 | 2022 | A rare frameshift mutation in SYCP1 is associated with human male infertility. | 3 |
| 29915389 | 2018 | Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. | 38 |
| 29915389 | 2018 | Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. | 38 |
| 27548613 | 2016 | Crystal Structure of C-Terminal Coiled-Coil Domain of SYCP1 Reveals Non-Canonical Anti-Parallel Dimeric Structure of Transverse Filament at the Synaptonemal Complex. | 5 |
| 27548613 | 2016 | Crystal Structure of C-Terminal Coiled-Coil Domain of SYCP1 Reveals Non-Canonical Anti-Parallel Dimeric Structure of Transverse Filament at the Synaptonemal Complex. | 5 |
| 26323297 | 2015 | X-ray crystallographic studies of the middle part of the human synaptonemal complex protein 1 coiled-coil domain. | 1 |
| 26323297 | 2015 | X-ray crystallographic studies of the middle part of the human synaptonemal complex protein 1 coiled-coil domain. | 1 |
| 24850846 | 2014 | Ectopic expression of cancer-testis antigens in cutaneous T-cell lymphoma patients. | 29 |
| 24850846 | 2014 | Ectopic expression of cancer-testis antigens in cutaneous T-cell lymphoma patients. | 29 |
| 20378615 | 2010 | Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. | 61 |
| 20800603 | 2010 | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. | 14 |
| 20378615 | 2010 | Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. | 61 |
| 20800603 | 2010 | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. | 14 |
| 17608150 | 2007 | [Expression of cancer-testis antigen SCP-1 mRNA in human nasopharyngeal carcinoma]. | 1 |
Citation
Dessen P
SYCP1 (synaptonemal complex protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46452/sycp1
