Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23336
MIM: 606087
HGNC: 24466
Ensembl: ENSG00000182253
Variants:
dbSNP: 23336
ClinVar: 23336
TCGA: ENSG00000182253
COSMIC: SYNM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182253 | ENST00000328642 | C9JIE4 |
| ENSG00000182253 | ENST00000336292 | O15061 |
| ENSG00000182253 | ENST00000560674 | H0YL34 |
| ENSG00000182253 | ENST00000594047 | A0A075B7B1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35361267 | 2022 | A risk model of gene signatures for predicting platinum response and survival in ovarian cancer. | 9 |
| 35769011 | 2022 | Synemin promotes pulmonary artery smooth muscle cell phenotypic switch in shunt-induced pulmonary arterial hypertension. | 4 |
| 35361267 | 2022 | A risk model of gene signatures for predicting platinum response and survival in ovarian cancer. | 9 |
| 35769011 | 2022 | Synemin promotes pulmonary artery smooth muscle cell phenotypic switch in shunt-induced pulmonary arterial hypertension. | 4 |
| 33019757 | 2020 | c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair. | 5 |
| 33019757 | 2020 | c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair. | 5 |
| 30276801 | 2019 | A novel heterozygous variant p.(Trp538Arg) of SYNM is identified by whole-exome sequencing in a Chinese family with dilated cardiomyopathy. | 5 |
| 31461342 | 2019 | Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators. | 11 |
| 30276801 | 2019 | A novel heterozygous variant p.(Trp538Arg) of SYNM is identified by whole-exome sequencing in a Chinese family with dilated cardiomyopathy. | 5 |
| 31461342 | 2019 | Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators. | 11 |
| 27470516 | 2016 | Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. | 40 |
| 27470516 | 2016 | Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. | 40 |
| 23594359 | 2014 | Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease. | 14 |
| 25447537 | 2014 | α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin. | 6 |
| 23594359 | 2014 | Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease. | 14 |
Citation
Dessen P
SYNM (synemin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/50031/synm
