SYT5 (synaptotagmin 5)

2007-02-01  

Identity

HGNC
SYT5
LOCATION
19q13.42
LOCUSID
6861
ALIAS
-

Other Information

Locus ID:

NCBI: 6861
MIM: 600782
HGNC: 11513
Ensembl: ENSG00000129990

Variants:

dbSNP: 6861
ClinVar: 6861
TCGA: ENSG00000129990
COSMIC: SYT5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129990ENST00000354308O00445
ENSG00000129990ENST00000354308A0A024R4N8
ENSG00000129990ENST00000537500O00445
ENSG00000129990ENST00000537500A0A024R4N8
ENSG00000129990ENST00000585461K7EJ95
ENSG00000129990ENST00000587067K7EJS7
ENSG00000129990ENST00000589172K7EQ59
ENSG00000129990ENST00000590851O00445
ENSG00000129990ENST00000590859M0QYJ7
ENSG00000129990ENST00000592470K7EJC4

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Integration of energy metabolismREACTOMER-HSA-163685
Regulation of insulin secretionREACTOMER-HSA-422356

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
204710302010Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.42
158207742005Evidence for the association of synaptotagmin with glutathione S-transferases: implications for a novel function in human breast cancer.5
221022352011Cloning, expression, purification, crystallization and preliminary X-ray diffraction crystallographic study of human synaptotagmin 5 C2A domain.0
277936832017Structural analysis of Ca2+-binding pocket of synaptotagmin 5 C2A domain.0

Citation

Dessen P

SYT5 (synaptotagmin 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46488/syt5