SYTL2 (synaptotagmin like 2)

2008-12-01  

Identity

HGNC
LOCATION
11q14.1
LOCUSID
ALIAS
CHR11SYT,EXO4,PPP1R151,SGA72M,SLP2,SLP2A
FUSION GENES

Other Information

Locus ID:

NCBI: 54843
MIM: 612880
HGNC: 15585
Ensembl: ENSG00000137501

Variants:

dbSNP: 54843
ClinVar: 54843
TCGA: ENSG00000137501
COSMIC: SYTL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137501ENST00000316356Q9HCH5
ENSG00000137501ENST00000354566A0A0U1RQP0
ENSG00000137501ENST00000359152Q9HCH5
ENSG00000137501ENST00000389958Q9HCH5
ENSG00000137501ENST00000389959A0A0U1RRJ3
ENSG00000137501ENST00000389960Q9HCH5
ENSG00000137501ENST00000524452Q9HCH5
ENSG00000137501ENST00000524911E9PS39
ENSG00000137501ENST00000525702Q9HCH5
ENSG00000137501ENST00000526999E9PRW5
ENSG00000137501ENST00000527523Q9HCH5
ENSG00000137501ENST00000527794E9PPL3
ENSG00000137501ENST00000528231Q9HCH5
ENSG00000137501ENST00000529534E9PS29
ENSG00000137501ENST00000529581Q9HCH5
ENSG00000137501ENST00000530351A0A0U1RQH1
ENSG00000137501ENST00000532221E9PK22
ENSG00000137501ENST00000532995E9PIB5
ENSG00000137501ENST00000533057E9PQL8
ENSG00000137501ENST00000533577A0A1Y8EH08
ENSG00000137501ENST00000533892Q9HCH5
ENSG00000137501ENST00000634661A0A0U1RR07

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376406702024Effects of COL1A1 and SYTL2 on inflammatory cell infiltration and poor extracellular matrix remodeling of the vascular wall in thoracic aortic aneurysm.0
376406702024Effects of COL1A1 and SYTL2 on inflammatory cell infiltration and poor extracellular matrix remodeling of the vascular wall in thoracic aortic aneurysm.0
371477132023SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.1
371477132023SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.1
338533522021Synaptotagmin-Like Protein 2a Regulates Angiogenic Lumen Formation via Weibel-Palade Body Apical Secretion of Angiopoietin-2.11
338533522021Synaptotagmin-Like Protein 2a Regulates Angiogenic Lumen Formation via Weibel-Palade Body Apical Secretion of Angiopoietin-2.11
272202832016Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer.11
272202832016Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer.11
206541572010[Relationship between SLP-2 expression and prognosis in laryngeal squamous cell carcinoma and mammary invasive carcinoma].2
207291992010Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.21
212236882010[Expression of SLP-2 protein in esophageal squamous cell carcinoma is associated with cancer invasion].0
206541572010[Relationship between SLP-2 expression and prognosis in laryngeal squamous cell carcinoma and mammary invasive carcinoma].2
207291992010Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.21
212236882010[Expression of SLP-2 protein in esophageal squamous cell carcinoma is associated with cancer invasion].0
182667822008Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.41

Citation

Dessen P

SYTL2 (synaptotagmin like 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50549/sytl2