Identity
HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
3-Tab1,MAP3K7IP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10454
MIM: 602615
HGNC: 18157
Ensembl: ENSG00000100324
Variants:
dbSNP: 10454
ClinVar: 10454
TCGA: ENSG00000100324
COSMIC: TAB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100324 | ENST00000216160 | Q15750 |
| ENSG00000100324 | ENST00000216160 | A8K6K3 |
| ENSG00000100324 | ENST00000331454 | Q15750 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36495029 | 2023 | Chlamydia trachomatis antigen induces TLR4-TAB1-mediated inflammation, but not cell death, in maternal decidua cells. | 1 |
| 37228128 | 2023 | Induction of pro-inflammatory genes by fibronectin DAMPs in three fibroblast cell lines: Role of TAK1 and MAP kinases. | 0 |
| 38072991 | 2023 | Down-regulated TAB1 suppresses the replication of Coxsackievirus B5 via activating the NF-κB pathways through interaction with viral 3D polymerase. | 0 |
| 36495029 | 2023 | Chlamydia trachomatis antigen induces TLR4-TAB1-mediated inflammation, but not cell death, in maternal decidua cells. | 1 |
| 37228128 | 2023 | Induction of pro-inflammatory genes by fibronectin DAMPs in three fibroblast cell lines: Role of TAK1 and MAP kinases. | 0 |
| 38072991 | 2023 | Down-regulated TAB1 suppresses the replication of Coxsackievirus B5 via activating the NF-κB pathways through interaction with viral 3D polymerase. | 0 |
| 33183761 | 2021 | Myeloma cells self-promote migration by regulating TAB1-driven TIMP-1 expression in mesenchymal stem cells. | 3 |
| 33183761 | 2021 | Myeloma cells self-promote migration by regulating TAB1-driven TIMP-1 expression in mesenchymal stem cells. | 3 |
| 30760523 | 2019 | G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. | 23 |
| 31115539 | 2019 | ΜicroRNA‑889 plays a suppressive role in cell proliferation and invasion by directly targeting TAB1 in non‑small cell lung cancer. | 6 |
| 30760523 | 2019 | G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells. | 23 |
| 31115539 | 2019 | ΜicroRNA‑889 plays a suppressive role in cell proliferation and invasion by directly targeting TAB1 in non‑small cell lung cancer. | 6 |
| 29229647 | 2018 | TAB1-Induced Autoactivation of p38α Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185. | 11 |
| 29328486 | 2018 | miR‑873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1. | 17 |
| 29893818 | 2018 | Oxidative stress-induced TGF-beta/TAB1-mediated p38MAPK activation in human amnion epithelial cells. | 38 |
Citation
Dessen P
TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-02-01
Online version: http://atlasgeneticsoncology.org/gene/51350/tab1
