TADA2A (transcriptional adaptor 2A)

2003-05-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
ADA2,ADA2A,KL04P,TADA2L,hADA2
FUSION GENES

Other Information

Locus ID:

NCBI: 6871
MIM: 602276
HGNC: 11531
Ensembl: ENSG00000276234

Variants:

dbSNP: 6871
ClinVar: 6871
TCGA: ENSG00000276234
COSMIC: TADA2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276234ENST00000612272A0A024R0Y4
ENSG00000276234ENST00000614112A0A087WU71
ENSG00000276234ENST00000614122A0A087WZS1
ENSG00000276234ENST00000615182A0A024R0Y4
ENSG00000276234ENST00000615328A0A087WTV5
ENSG00000276234ENST00000619777A0A087WYK3
ENSG00000276234ENST00000620367A0A087WWR4
ENSG00000276234ENST00000620628A0A024R0Y4
ENSG00000276234ENST00000621780A0A087X2C8

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

References

Pubmed IDYearTitleCitations
162995142005Structure and chromosomal DNA binding of the SWIRM domain.22
264682802015Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5.10
180591732008hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin.9
226443762012CCDC134 interacts with hADA2a and functions as a regulator of hADA2a in acetyltransferase activity, DNA damage-induced apoptosis and cell cycle arrest.4
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?2
254920862015Genetic factors adaptive in a malarial environment may increase the risk of type 1 diabetes.0

Citation

Dessen P

TADA2A (transcriptional adaptor 2A)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42461/tada2a