TAF3 (TATA-box binding protein associated factor 3)

2014-11-01  

Identity

HGNC
TAF3
LOCATION
10p14
LOCUSID
83860
ALIAS
TAF140,TAFII-140,TAFII140
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83860
MIM: 606576
HGNC: 17303
Ensembl: ENSG00000165632

Variants:

dbSNP: 83860
ClinVar: 83860
TCGA: ENSG00000165632
COSMIC: TAF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165632ENST00000344293Q5VWG9

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756

References

Pubmed IDYearTitleCitations
234528512013H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation.141
218849342011Control of embryonic stem cell lineage commitment by core promoter factor, TAF3.87
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
179751192008Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.65
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.16
185494812008TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function.11
208088252010Novel association strategy with copy number variation for identifying new risk Loci of human diseases.11
239359562013Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.8

Citation

Dessen P

TAF3 (TATA-box binding protein associated factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74469/taf3