TAF7 (TATA-box binding protein associated factor 7)

2003-05-01  

Identity

HGNC
LOCATION
5q31.3
LOCUSID
ALIAS
TAF2F,TAFII55
FUSION GENES

Other Information

Locus ID:

NCBI: 6879
MIM: 600573
HGNC: 11541
Ensembl: ENSG00000178913

Variants:

dbSNP: 6879
ClinVar: 6879
TCGA: ENSG00000178913
COSMIC: TAF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178913ENST00000313368Q15545
ENSG00000178913ENST00000624761A0A096LPC3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
230278732012Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation.24
183911972008TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.22
164071232006TAF7: a possible transcription initiation check-point regulator.20
254126592014Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.19
249275292014Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.15
209378242010Novel functions for TAF7, a regulator of TAF1-independent transcription.13
227119892012Phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7.12
255751202015MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.11
126769572003TAF7 (TAFII55) plays a role in the transcription activation by c-Jun.10
150788712004TATA-binding protein-associated factor 7 regulates polyamine transport activity and polyamine analog-induced apoptosis.3

Citation

Dessen P

TAF7 (TATA-box binding protein associated factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42465/taf7