TAF7 (TATA-box binding protein associated factor 7)

2003-05-01  

Identity

HGNC
LOCATION
5q31.3
LOCUSID
ALIAS
TAF2F,TAFII55
FUSION GENES

Other Information

Locus ID:

NCBI: 6879
MIM: 600573
HGNC: 11541
Ensembl: ENSG00000178913

Variants:

dbSNP: 6879
ClinVar: 6879
TCGA: ENSG00000178913
COSMIC: TAF7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178913ENST00000313368Q15545
ENSG00000178913ENST00000624761A0A096LPC3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
347622732021Novel variations in spermatogenic transcription regulators RFX2 and TAF7 increase risk of azoospermia.1
347622732021Novel variations in spermatogenic transcription regulators RFX2 and TAF7 increase risk of azoospermia.1
311627142019MicroRNA-374c-5p inhibits the development of breast cancer through TATA-box binding protein associated factor 7-mediated transcriptional regulation of DEP domain containing 1.13
311627142019MicroRNA-374c-5p inhibits the development of breast cancer through TATA-box binding protein associated factor 7-mediated transcriptional regulation of DEP domain containing 1.13
300280802018TAF7 is a heat-inducible unstable protein and is required for sustained expression of heat shock protein genes.2
300280802018TAF7 is a heat-inducible unstable protein and is required for sustained expression of heat shock protein genes.2
288935342017Solution Structure of the N-Terminal Domain of Mediator Subunit MED26 and Molecular Characterization of Its Interaction with EAF1 and TAF7.8
288935342017Solution Structure of the N-Terminal Domain of Mediator Subunit MED26 and Molecular Characterization of Its Interaction with EAF1 and TAF7.8
255751202015MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.21
255751202015MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.21
249275292014Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.22
254126592014Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.30
249275292014Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.22
254126592014Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.30
227119892012Phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7.21

Citation

Dessen P

TAF7 (TATA-box binding protein associated factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42465/taf7