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TAFA4 (TAFA chemokine like family member 4)

Identity

Alias_namesFAM19A4
family with sequence similarity 19 member A4, C-C motif chemokine like
Alias_symbol (synonym)TAFA-4
Other alias
HGNC (Hugo) TAFA4
LocusID (NCBI) 151647
Atlas_Id 55341
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 68731764 and ends at 68932610 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM19A4 3p14.1 / CACNA2D3 3p21.1FHIT 3p14.2 / FAM19A4 3p14.1
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  FAM19A4/TMF1 (3p14)
FHIT/FAM19A4 (3p14)
t(3;3)(p14;p21) FAM19A4/CACNA2D3


External links

Nomenclature
HGNC (Hugo)TAFA4   21591
Cards
Entrez_Gene (NCBI)TAFA4  151647  TAFA chemokine like family member 4
AliasesFAM19A4; TAFA-4
GeneCards (Weizmann)TAFA4
Ensembl hg19 (Hinxton)ENSG00000163377 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163377 [Gene_View]  ENSG00000163377 [Sequence]  chr3:68731764-68932610 [Contig_View]  TAFA4 [Vega]
ICGC DataPortalENSG00000163377
TCGA cBioPortalTAFA4
AceView (NCBI)TAFA4
Genatlas (Paris)TAFA4
WikiGenes151647
SOURCE (Princeton)TAFA4
Genetics Home Reference (NIH)TAFA4
Genomic and cartography
GoldenPath hg38 (UCSC)TAFA4  -     chr3:68731764-68932610 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAFA4  -     -   [Description]    (hg19-Feb_2009)
GoldenPathTAFA4 - - [CytoView hg19]  TAFA4 - - [CytoView hg38]
ImmunoBaseENSG00000163377
Mapping of homologs : NCBITAFA4 [Mapview hg19]  TAFA4 [Mapview hg38]
OMIM617498   
Gene and transcription
Genbank (Entrez)AK057890 AY325117 BC031566 DA017279
RefSeq transcript (Entrez)NM_001005527 NM_182522
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAFA4
Cluster EST : UnigeneHs.736925 [ NCBI ]
CGAP (NCI)Hs.736925
Alternative Splicing GalleryENSG00000163377
Gene ExpressionTAFA4 [ NCBI-GEO ]   TAFA4 [ EBI - ARRAY_EXPRESS ]   TAFA4 [ SEEK ]   TAFA4 [ MEM ]
Gene Expression Viewer (FireBrowse)TAFA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151647
GTEX Portal (Tissue expression)TAFA4
Human Protein AtlasENSG00000163377-TAFA4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LR4
Splice isoforms : SwissVarQ96LR4
PhosPhoSitePlusQ96LR4
Domains : Interpro (EBI)Chemokine-like_FAM19A2   
Domain families : Pfam (Sanger)TAFA (PF12020)   
Domain families : Pfam (NCBI)pfam12020   
Domain structure : Prodom (Prabi Lyon)Chemokine-like_2FAM19A2 (PD298472)   
Conserved Domain (NCBI)TAFA4
DMDM Disease mutations151647
Blocks (Seattle)TAFA4
SuperfamilyQ96LR4
Human Protein Atlas [tissue]ENSG00000163377-TAFA4 [tissue]
Peptide AtlasQ96LR4
HPRD08343
IPIIPI00065186   IPI00945666   
Protein Interaction databases
DIP (DOE-UCLA)Q96LR4
IntAct (EBI)Q96LR4
FunCoupENSG00000163377
BioGRIDTAFA4
STRING (EMBL)TAFA4
ZODIACTAFA4
Ontologies - Pathways
QuickGOQ96LR4
Ontology : AmiGOprotein binding  extracellular space  extracellular space  phagocytosis  phagocytosis  signal transduction  regulation of signaling receptor activity  regulation of membrane potential  superoxide anion generation  receptor ligand activity  receptor ligand activity  macrophage chemotaxis  macrophage chemotaxis  regulation of sensory perception of pain  
Ontology : EGO-EBIprotein binding  extracellular space  extracellular space  phagocytosis  phagocytosis  signal transduction  regulation of signaling receptor activity  regulation of membrane potential  superoxide anion generation  receptor ligand activity  receptor ligand activity  macrophage chemotaxis  macrophage chemotaxis  regulation of sensory perception of pain  
NDEx NetworkTAFA4
Atlas of Cancer Signalling NetworkTAFA4
Wikipedia pathwaysTAFA4
Orthology - Evolution
OrthoDB151647
GeneTree (enSembl)ENSG00000163377
Phylogenetic Trees/Animal Genes : TreeFamTAFA4
HOGENOMQ96LR4
Homologs : HomoloGeneTAFA4
Homology/Alignments : Family Browser (UCSC)TAFA4
Gene fusions - Rearrangements
Fusion : MitelmanFAM19A4/CACNA2D3 [3p14.1/3p21.1]  
Fusion : MitelmanFHIT/FAM19A4 [3p14.2/3p14.1]  [t(3;3)(p14;p14)]  
Fusion PortalFAM19A4 3p14.1 CACNA2D3 3p21.1 BRCA
Fusion PortalFHIT 3p14.2 FAM19A4 3p14.1 LUAD
Fusion : QuiverTAFA4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAFA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAFA4
dbVarTAFA4
ClinVarTAFA4
1000_GenomesTAFA4 
Exome Variant ServerTAFA4
ExAC (Exome Aggregation Consortium)ENSG00000163377
GNOMAD BrowserENSG00000163377
Varsome BrowserTAFA4
Genetic variants : HAPMAP151647
Genomic Variants (DGV)TAFA4 [DGVbeta]
DECIPHERTAFA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAFA4 
Mutations
ICGC Data PortalTAFA4 
TCGA Data PortalTAFA4 
Broad Tumor PortalTAFA4
OASIS PortalTAFA4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTAFA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAFA4
DgiDB (Drug Gene Interaction Database)TAFA4
DoCM (Curated mutations)TAFA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAFA4 (select a term)
intoGenTAFA4
Cancer3DTAFA4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617498   
Orphanet
DisGeNETTAFA4
MedgenTAFA4
Genetic Testing Registry TAFA4
NextProtQ96LR4 [Medical]
TSGene151647
GENETestsTAFA4
Target ValidationTAFA4
Huge Navigator TAFA4 [HugePedia]
snp3D : Map Gene to Disease151647
BioCentury BCIQTAFA4
ClinGenTAFA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151647
Chemical/Pharm GKB GenePA134873006
Clinical trialTAFA4
Miscellaneous
canSAR (ICR)TAFA4 (select the gene name)
DataMed IndexTAFA4
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAFA4
EVEXTAFA4
GoPubMedTAFA4
iHOPTAFA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:10:45 CET 2019

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