Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
MAP3K17,PSK,PSK1,PSK1-BETA,TAO1,TAO2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9344
MIM: 613199
HGNC: 16835
Ensembl: ENSG00000149930
Variants:
dbSNP: 9344
ClinVar: 9344
TCGA: ENSG00000149930
COSMIC: TAOK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000149930 | ENST00000279394 | Q9UL54 |
| ENSG00000149930 | ENST00000308893 | Q9UL54 |
| ENSG00000149930 | ENST00000416441 | Q9UL54 |
| ENSG00000149930 | ENST00000543033 | Q9UL54 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37813295 | 2024 | Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth. | 0 |
| 37813295 | 2024 | Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth. | 0 |
| 34879262 | 2021 | TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules. | 7 |
| 35141166 | 2021 | The circRNA circSIAE Inhibits Replication of Coxsackie Virus B3 by Targeting miR-331-3p and Thousand and One Amino-Acid Kinase 2. | 10 |
| 34879262 | 2021 | TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules. | 7 |
| 35141166 | 2021 | The circRNA circSIAE Inhibits Replication of Coxsackie Virus B3 by Targeting miR-331-3p and Thousand and One Amino-Acid Kinase 2. | 10 |
| 28830982 | 2017 | Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. | 24 |
| 28830982 | 2017 | Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. | 24 |
| 23585562 | 2013 | Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. | 29 |
| 23585562 | 2013 | Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. | 29 |
| 22683681 | 2012 | Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. | 96 |
| 22683681 | 2012 | Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. | 96 |
| 19242545 | 2009 | Association and mutation analyses of 16p11.2 autism candidate genes. | 45 |
| 19242545 | 2009 | Association and mutation analyses of 16p11.2 autism candidate genes. | 45 |
| 17158878 | 2007 | Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing. | 20 |
Citation
Dessen P
TAOK2 (TAO kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-06-01
Online version: http://atlasgeneticsoncology.org/gene/47560/taok2
