Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
NGS17,TAPA,TPN,TPSN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6892
MIM: 601962
HGNC: 11566
Ensembl: ENSG00000231925
Variants:
dbSNP: 6892
ClinVar: 6892
TCGA: ENSG00000231925
COSMIC: TAPBP
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 23736108 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 23736108 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38516804 | 2024 | The downregulation of Tapasin in dendritic cell regulates CD8(+) T cell autophagy to hamper hepatitis B viral clearance in the induced pluripotent stem cell-derived hepatocyte organoid. | 0 |
| 38948930 | 2024 | Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma. | 0 |
| 38516804 | 2024 | The downregulation of Tapasin in dendritic cell regulates CD8(+) T cell autophagy to hamper hepatitis B viral clearance in the induced pluripotent stem cell-derived hepatocyte organoid. | 0 |
| 38948930 | 2024 | Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma. | 0 |
| 35858344 | 2022 | Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner. | 1 |
| 35858344 | 2022 | Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner. | 1 |
| 34244493 | 2021 | Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules. | 19 |
| 34265495 | 2021 | The role of MHC I protein dynamics in tapasin and TAPBPR-assisted immunopeptidome editing. | 10 |
| 34244493 | 2021 | Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules. | 19 |
| 34265495 | 2021 | The role of MHC I protein dynamics in tapasin and TAPBPR-assisted immunopeptidome editing. | 10 |
| 32788370 | 2020 | Atomistic structure and dynamics of the human MHC-I peptide-loading complex. | 29 |
| 33097667 | 2020 | HLA tapasin independence: broader peptide repertoire and HIV control. | 34 |
| 32788370 | 2020 | Atomistic structure and dynamics of the human MHC-I peptide-loading complex. | 29 |
| 33097667 | 2020 | HLA tapasin independence: broader peptide repertoire and HIV control. | 34 |
| 26754481 | 2016 | Molecular mechanism of peptide editing in the tapasin-MHC I complex. | 33 |
Citation
Dessen P
TAPBP (TAP binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42470/tapbp
