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TAS2R14 (taste 2 receptor member 14)

Identity

Alias_namestaste receptor, type 2, member 14
Alias_symbol (synonym)T2R14
TRB1
Other alias
HGNC (Hugo) TAS2R14
LocusID (NCBI) 50840
Atlas_Id 51583
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10938254 and ends at 10939207 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TAS2R14   14920
Cards
Entrez_Gene (NCBI)TAS2R14  50840  taste 2 receptor member 14
AliasesT2R14; TRB1
GeneCards (Weizmann)TAS2R14
Ensembl hg19 (Hinxton)ENSG00000212127 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000212127 [Gene_View]  ENSG00000212127 [Sequence]  chr12:10938254-10939207 [Contig_View]  TAS2R14 [Vega]
ICGC DataPortalENSG00000212127
TCGA cBioPortalTAS2R14
AceView (NCBI)TAS2R14
Genatlas (Paris)TAS2R14
WikiGenes50840
SOURCE (Princeton)TAS2R14
Genetics Home Reference (NIH)TAS2R14
Genomic and cartography
GoldenPath hg38 (UCSC)TAS2R14  -     chr12:10938254-10939207 -  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS2R14  -     12p13.2   [Description]    (hg19-Feb_2009)
GoldenPathTAS2R14 - 12p13.2 [CytoView hg19]  TAS2R14 - 12p13.2 [CytoView hg38]
ImmunoBaseENSG00000212127
Mapping of homologs : NCBITAS2R14 [Mapview hg19]  TAS2R14 [Mapview hg38]
OMIM604790   
Gene and transcription
Genbank (Entrez)BC069148 BC101993 BC101994 BC103699
RefSeq transcript (Entrez)NM_023922
RefSeq genomic (Entrez)NC_000012 NT_187658 NW_003571050
Consensus coding sequences : CCDS (NCBI)TAS2R14
Cluster EST : UnigeneHs.679406 [ NCBI ]
CGAP (NCI)Hs.679406
Alternative Splicing GalleryENSG00000212127
Gene ExpressionTAS2R14 [ NCBI-GEO ]   TAS2R14 [ EBI - ARRAY_EXPRESS ]   TAS2R14 [ SEEK ]   TAS2R14 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS2R14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50840
GTEX Portal (Tissue expression)TAS2R14
Human Protein AtlasENSG00000212127-TAS2R14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYV8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYV8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYV8
Splice isoforms : SwissVarQ9NYV8
PhosPhoSitePlusQ9NYV8
Domains : Interpro (EBI)T2R   
Domain families : Pfam (Sanger)TAS2R (PF05296)   
Domain families : Pfam (NCBI)pfam05296   
Conserved Domain (NCBI)TAS2R14
DMDM Disease mutations50840
Blocks (Seattle)TAS2R14
SuperfamilyQ9NYV8
Human Protein Atlas [tissue]ENSG00000212127-TAS2R14 [tissue]
Peptide AtlasQ9NYV8
HPRD11989
IPIIPI00028350   IPI00845431   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYV8
IntAct (EBI)Q9NYV8
FunCoupENSG00000212127
BioGRIDTAS2R14
STRING (EMBL)TAS2R14
ZODIACTAS2R14
Ontologies - Pathways
QuickGOQ9NYV8
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  taste receptor activity  taste receptor activity  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  taste receptor activity  taste receptor activity  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS2R14
Atlas of Cancer Signalling NetworkTAS2R14
Wikipedia pathwaysTAS2R14
Orthology - Evolution
OrthoDB50840
GeneTree (enSembl)ENSG00000212127
Phylogenetic Trees/Animal Genes : TreeFamTAS2R14
HOGENOMQ9NYV8
Homologs : HomoloGeneTAS2R14
Homology/Alignments : Family Browser (UCSC)TAS2R14
Gene fusions - Rearrangements
Fusion : QuiverTAS2R14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS2R14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS2R14
dbVarTAS2R14
ClinVarTAS2R14
1000_GenomesTAS2R14 
Exome Variant ServerTAS2R14
ExAC (Exome Aggregation Consortium)ENSG00000212127
GNOMAD BrowserENSG00000212127
Varsome BrowserTAS2R14
Genetic variants : HAPMAP50840
Genomic Variants (DGV)TAS2R14 [DGVbeta]
DECIPHERTAS2R14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS2R14 
Mutations
ICGC Data PortalTAS2R14 
TCGA Data PortalTAS2R14 
Broad Tumor PortalTAS2R14
OASIS PortalTAS2R14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS2R14  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAS2R14
Mutations and Diseases : HGMDTAS2R14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAS2R14
DgiDB (Drug Gene Interaction Database)TAS2R14
DoCM (Curated mutations)TAS2R14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAS2R14 (select a term)
intoGenTAS2R14
Cancer3DTAS2R14(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604790   
Orphanet
DisGeNETTAS2R14
MedgenTAS2R14
Genetic Testing Registry TAS2R14
NextProtQ9NYV8 [Medical]
TSGene50840
GENETestsTAS2R14
Target ValidationTAS2R14
Huge Navigator TAS2R14 [HugePedia]
snp3D : Map Gene to Disease50840
BioCentury BCIQTAS2R14
ClinGenTAS2R14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50840
Chemical/Pharm GKB GenePA37930
Clinical trialTAS2R14
Miscellaneous
canSAR (ICR)TAS2R14 (select the gene name)
DataMed IndexTAS2R14
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAS2R14
EVEXTAS2R14
GoPubMedTAS2R14
iHOPTAS2R14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:10:50 CET 2019
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