TAS2R39 (taste 2 receptor member 39)

2014-11-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
T2R39,T2R57

Other Information

Locus ID:

NCBI: 259285
HGNC: 18886
Ensembl: ENSG00000236398

Variants:

dbSNP: 259285
ClinVar: 259285
TCGA: ENSG00000236398
COSMIC: TAS2R39

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000236398ENST00000446620P59534

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
219424222011Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39.12
216705122011Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides.3
212725672011Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.0
252731422014The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins.0

Citation

Dessen P

TAS2R39 (taste 2 receptor member 39)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74495/tas2r39