Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TAS2R40 (taste 2 receptor member 40)

Identity

Alias_namesGPR60
G protein-coupled receptor 60
taste receptor, type 2, member 40
Other aliasT2R40
T2R58
HGNC (Hugo) TAS2R40
LocusID (NCBI) 259286
Atlas_Id 74497
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 143222037 and ends at 143223079 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TAS2R40   18885
Cards
Entrez_Gene (NCBI)TAS2R40  259286  taste 2 receptor member 40
AliasesGPR60; T2R40; T2R58
GeneCards (Weizmann)TAS2R40
Ensembl hg19 (Hinxton)ENSG00000221937 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000221937 [Gene_View]  ENSG00000221937 [Sequence]  chr7:143222037-143223079 [Contig_View]  TAS2R40 [Vega]
ICGC DataPortalENSG00000221937
TCGA cBioPortalTAS2R40
AceView (NCBI)TAS2R40
Genatlas (Paris)TAS2R40
WikiGenes259286
SOURCE (Princeton)TAS2R40
Genetics Home Reference (NIH)TAS2R40
Genomic and cartography
GoldenPath hg38 (UCSC)TAS2R40  -     chr7:143222037-143223079 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAS2R40  -     7q34   [Description]    (hg19-Feb_2009)
GoldenPathTAS2R40 - 7q34 [CytoView hg19]  TAS2R40 - 7q34 [CytoView hg38]
ImmunoBaseENSG00000221937
genome Data Viewer NCBITAS2R40 [Mapview hg19]  
OMIM613964   
Gene and transcription
Genbank (Entrez)BC101795 BC101797
RefSeq transcript (Entrez)NM_176882
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAS2R40
Alternative Splicing GalleryENSG00000221937
Gene ExpressionTAS2R40 [ NCBI-GEO ]   TAS2R40 [ EBI - ARRAY_EXPRESS ]   TAS2R40 [ SEEK ]   TAS2R40 [ MEM ]
Gene Expression Viewer (FireBrowse)TAS2R40 [ Firebrowse - Broad ]
GenevisibleExpression of TAS2R40 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)259286
GTEX Portal (Tissue expression)TAS2R40
Human Protein AtlasENSG00000221937-TAS2R40 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP59535   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP59535  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP59535
Splice isoforms : SwissVarP59535
PhosPhoSitePlusP59535
Domains : Interpro (EBI)T2R   
Domain families : Pfam (Sanger)TAS2R (PF05296)   
Domain families : Pfam (NCBI)pfam05296   
Conserved Domain (NCBI)TAS2R40
DMDM Disease mutations259286
Blocks (Seattle)TAS2R40
SuperfamilyP59535
Human Protein Atlas [tissue]ENSG00000221937-TAS2R40 [tissue]
Peptide AtlasP59535
HPRD18150
IPIIPI00221131   
Protein Interaction databases
DIP (DOE-UCLA)P59535
IntAct (EBI)P59535
FunCoupENSG00000221937
BioGRIDTAS2R40
STRING (EMBL)TAS2R40
ZODIACTAS2R40
Ontologies - Pathways
QuickGOP59535
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  detection of chemical stimulus involved in sensory perception of bitter taste  G protein-coupled receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  integral component of membrane  bitter taste receptor activity  bitter taste receptor activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTAS2R40
Atlas of Cancer Signalling NetworkTAS2R40
Wikipedia pathwaysTAS2R40
Orthology - Evolution
OrthoDB259286
GeneTree (enSembl)ENSG00000221937
Phylogenetic Trees/Animal Genes : TreeFamTAS2R40
HOGENOMP59535
Homologs : HomoloGeneTAS2R40
Homology/Alignments : Family Browser (UCSC)TAS2R40
Gene fusions - Rearrangements
Fusion : QuiverTAS2R40
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAS2R40 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAS2R40
dbVarTAS2R40
ClinVarTAS2R40
1000_GenomesTAS2R40 
Exome Variant ServerTAS2R40
GNOMAD BrowserENSG00000221937
Varsome BrowserTAS2R40
Genetic variants : HAPMAP259286
Genomic Variants (DGV)TAS2R40 [DGVbeta]
DECIPHERTAS2R40 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAS2R40 
Mutations
ICGC Data PortalTAS2R40 
TCGA Data PortalTAS2R40 
Broad Tumor PortalTAS2R40
OASIS PortalTAS2R40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAS2R40  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAS2R40
Mutations and Diseases : HGMDTAS2R40
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAS2R40
DgiDB (Drug Gene Interaction Database)TAS2R40
DoCM (Curated mutations)TAS2R40 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAS2R40 (select a term)
intoGenTAS2R40
Cancer3DTAS2R40(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613964   
Orphanet
DisGeNETTAS2R40
MedgenTAS2R40
Genetic Testing Registry TAS2R40
NextProtP59535 [Medical]
TSGene259286
GENETestsTAS2R40
Target ValidationTAS2R40
Huge Navigator TAS2R40 [HugePedia]
snp3D : Map Gene to Disease259286
BioCentury BCIQTAS2R40
ClinGenTAS2R40
Clinical trials, drugs, therapy
Protein Interactions : CTD259286
Pharm GKB GenePA38738
Clinical trialTAS2R40
Miscellaneous
canSAR (ICR)TAS2R40 (select the gene name)
HarmonizomeTAS2R40
DataMed IndexTAS2R40
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAS2R40
EVEXTAS2R40
GoPubMedTAS2R40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jul 10 20:40:07 CEST 2020
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