TAS2R50 (taste 2 receptor member 50)

2014-11-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
T2R50,T2R51,TAS2R51

Other Information

Locus ID:

NCBI: 259296
MIM: 609627
HGNC: 18882
Ensembl: ENSG00000212126

Variants:

dbSNP: 259296
ClinVar: 259296
TCGA: ENSG00000212126
COSMIC: TAS2R50

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000212126ENST00000506868P59544

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
179751192008Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.65
161755052005Identification of four gene variants associated with myocardial infarction.44
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.16
221925112012KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.12
197097662011Variations of specific non-candidate genes and risk of myocardial infarction: a replication study.6
179676052007Associations with myocardial infarction of six polymorphisms selected from a three-stage genome-wide association study.4
283667702017A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.3
198174112009The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin.0

Citation

Dessen P

TAS2R50 (taste 2 receptor member 50)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74503/tas2r50