TBCA (tubulin folding cofactor A)

2014-11-01  

Identity

HGNC
TBCA
LOCATION
5q14.1
LOCUSID
6902
ALIAS
-

Other Information

Locus ID:

NCBI: 6902
MIM: 610058
HGNC: 11579
Ensembl: ENSG00000171530

Variants:

dbSNP: 6902
ClinVar: 6902
TCGA: ENSG00000171530
COSMIC: TBCA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171530ENST00000306388O75347
ENSG00000171530ENST00000380377O75347
ENSG00000171530ENST00000380377Q6FGD7
ENSG00000171530ENST00000517679E5RJD8
ENSG00000171530ENST00000518338E5RHG6
ENSG00000171530ENST00000520039E5RJM1
ENSG00000171530ENST00000520361E5RIX8
ENSG00000171530ENST00000522370E5RIW3
ENSG00000171530ENST00000651106A0A494C144

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Post-chaperonin tubulin folding pathwayREACTOMER-HSA-389977

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45
209507862010A genome-wide study reveals copy number variants exclusive to childhood obesity cases.41
237406432013Tubulin cofactor A functions as a novel positive regulator of ccRCC progression, invasion and metastasis.17
159635122005Tubulin cofactor A gene silencing in mammalian cells induces changes in microtubule cytoskeleton, cell cycle arrest and cell death.15

Citation

Dessen P

TBCA (tubulin folding cofactor A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74540/tbca