Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TBX10 (T-box transcription factor 10)

Identity

Alias_namesTBX7
T-box 7
Alias_symbol (synonym)TBX13
Other alias
HGNC (Hugo) TBX10
LocusID (NCBI) 347853
Atlas_Id 74551
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 67631303 and ends at 67639560 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TBX10   11593
Cards
Entrez_Gene (NCBI)TBX10  347853  T-box transcription factor 10
AliasesTBX13; TBX7
GeneCards (Weizmann)TBX10
Ensembl hg19 (Hinxton)ENSG00000167800 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167800 [Gene_View]  ENSG00000167800 [Sequence]  chr11:67631303-67639560 [Contig_View]  TBX10 [Vega]
ICGC DataPortalENSG00000167800
TCGA cBioPortalTBX10
AceView (NCBI)TBX10
Genatlas (Paris)TBX10
WikiGenes347853
SOURCE (Princeton)TBX10
Genetics Home Reference (NIH)TBX10
Genomic and cartography
GoldenPath hg38 (UCSC)TBX10  -     chr11:67631303-67639560 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TBX10  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathTBX10 - 11q13.2 [CytoView hg19]  TBX10 - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000167800
Mapping of homologs : NCBITBX10 [Mapview hg19]  TBX10 [Mapview hg38]
OMIM604648   
Gene and transcription
Genbank (Entrez)AY229977 BC113485 BC113487
RefSeq transcript (Entrez)NM_005995
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TBX10
Cluster EST : UnigeneHs.454480 [ NCBI ]
CGAP (NCI)Hs.454480
Alternative Splicing GalleryENSG00000167800
Gene ExpressionTBX10 [ NCBI-GEO ]   TBX10 [ EBI - ARRAY_EXPRESS ]   TBX10 [ SEEK ]   TBX10 [ MEM ]
Gene Expression Viewer (FireBrowse)TBX10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)347853
GTEX Portal (Tissue expression)TBX10
Human Protein AtlasENSG00000167800-TBX10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75333   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75333  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75333
Splice isoforms : SwissVarO75333
PhosPhoSitePlusO75333
Domaine pattern : Prosite (Expaxy)TBOX_1 (PS01283)    TBOX_2 (PS01264)    TBOX_3 (PS50252)   
Domains : Interpro (EBI)p53-like_TF_DNA-bd    T-box_sf    TF_T-box    TF_T-box_CS   
Domain families : Pfam (Sanger)T-box (PF00907)   
Domain families : Pfam (NCBI)pfam00907   
Domain families : Smart (EMBL)TBOX (SM00425)  
Conserved Domain (NCBI)TBX10
DMDM Disease mutations347853
Blocks (Seattle)TBX10
SuperfamilyO75333
Human Protein Atlas [tissue]ENSG00000167800-TBX10 [tissue]
Peptide AtlasO75333
HPRD06872
IPIIPI00385367   
Protein Interaction databases
DIP (DOE-UCLA)O75333
IntAct (EBI)O75333
FunCoupENSG00000167800
BioGRIDTBX10
STRING (EMBL)TBX10
ZODIACTBX10
Ontologies - Pathways
QuickGOO75333
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase II activating transcription factor binding  DNA-binding transcription activator activity, RNA polymerase II-specific  cell fate specification  DNA binding  nucleus  nucleus  regulation of transcription by RNA polymerase II  anatomical structure morphogenesis  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  RNA polymerase II activating transcription factor binding  DNA-binding transcription activator activity, RNA polymerase II-specific  cell fate specification  DNA binding  nucleus  nucleus  regulation of transcription by RNA polymerase II  anatomical structure morphogenesis  positive regulation of transcription by RNA polymerase II  
NDEx NetworkTBX10
Atlas of Cancer Signalling NetworkTBX10
Wikipedia pathwaysTBX10
Orthology - Evolution
OrthoDB347853
GeneTree (enSembl)ENSG00000167800
Phylogenetic Trees/Animal Genes : TreeFamTBX10
HOGENOMO75333
Homologs : HomoloGeneTBX10
Homology/Alignments : Family Browser (UCSC)TBX10
Gene fusions - Rearrangements
Fusion : QuiverTBX10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTBX10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TBX10
dbVarTBX10
ClinVarTBX10
1000_GenomesTBX10 
Exome Variant ServerTBX10
ExAC (Exome Aggregation Consortium)ENSG00000167800
GNOMAD BrowserENSG00000167800
Varsome BrowserTBX10
Genetic variants : HAPMAP347853
Genomic Variants (DGV)TBX10 [DGVbeta]
DECIPHERTBX10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTBX10 
Mutations
ICGC Data PortalTBX10 
TCGA Data PortalTBX10 
Broad Tumor PortalTBX10
OASIS PortalTBX10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTBX10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTBX10
Mutations and Diseases : HGMDTBX10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TBX10
DgiDB (Drug Gene Interaction Database)TBX10
DoCM (Curated mutations)TBX10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TBX10 (select a term)
intoGenTBX10
Cancer3DTBX10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604648   
Orphanet
DisGeNETTBX10
MedgenTBX10
Genetic Testing Registry TBX10
NextProtO75333 [Medical]
TSGene347853
GENETestsTBX10
Target ValidationTBX10
Huge Navigator TBX10 [HugePedia]
snp3D : Map Gene to Disease347853
BioCentury BCIQTBX10
ClinGenTBX10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD347853
Chemical/Pharm GKB GenePA36356
Clinical trialTBX10
Miscellaneous
canSAR (ICR)TBX10 (select the gene name)
DataMed IndexTBX10
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTBX10
EVEXTBX10
GoPubMedTBX10
iHOPTBX10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:09:28 CEST 2019

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