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TCAF1 (TRPM8 channel associated factor 1)

Identity

Alias_namesFAM115A
family with sequence similarity 115, member A
TRPM8 channel-associated factor 1
Alias_symbol (synonym)KIAA0738
Other alias
HGNC (Hugo) TCAF1
LocusID (NCBI) 9747
Atlas_Id 55663
Location 7q35  [Link to chromosome band 7q35]
Location_base_pair Starts at 143851368 and ends at 143902079 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TCAF1 (7q35) / BAIAP2L1 (7q21.3)TCAF1 (7q35) / SDCCAG8 (1q43)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TCAF1   22201
Cards
Entrez_Gene (NCBI)TCAF1  9747  TRPM8 channel associated factor 1
AliasesFAM115A
GeneCards (Weizmann)TCAF1
Ensembl hg19 (Hinxton)ENSG00000198420 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198420 [Gene_View]  ENSG00000198420 [Sequence]  chr7:143851368-143902079 [Contig_View]  TCAF1 [Vega]
ICGC DataPortalENSG00000198420
TCGA cBioPortalTCAF1
AceView (NCBI)TCAF1
Genatlas (Paris)TCAF1
WikiGenes9747
SOURCE (Princeton)TCAF1
Genetics Home Reference (NIH)TCAF1
Genomic and cartography
GoldenPath hg38 (UCSC)TCAF1  -     chr7:143851368-143902079 -  7q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCAF1  -     7q35   [Description]    (hg19-Feb_2009)
GoldenPathTCAF1 - 7q35 [CytoView hg19]  TCAF1 - 7q35 [CytoView hg38]
ImmunoBaseENSG00000198420
Mapping of homologs : NCBITCAF1 [Mapview hg19]  TCAF1 [Mapview hg38]
OMIM616251   
Gene and transcription
Genbank (Entrez)AB018281 AF086218 AF119896 AK001640 AK291605
RefSeq transcript (Entrez)NM_001206938 NM_001206941 NM_014719
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TCAF1
Cluster EST : UnigeneHs.744048 [ NCBI ]
CGAP (NCI)Hs.744048
Alternative Splicing GalleryENSG00000198420
Gene ExpressionTCAF1 [ NCBI-GEO ]   TCAF1 [ EBI - ARRAY_EXPRESS ]   TCAF1 [ SEEK ]   TCAF1 [ MEM ]
Gene Expression Viewer (FireBrowse)TCAF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9747
GTEX Portal (Tissue expression)TCAF1
Human Protein AtlasENSG00000198420-TCAF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4C2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4C2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4C2
Splice isoforms : SwissVarQ9Y4C2
PhosPhoSitePlusQ9Y4C2
Domaine pattern : Prosite (Expaxy)PEPTIDASE_M60 (PS51723)   
Domains : Interpro (EBI)Class_I_gatase-like    M60-like_N    Peptidase_M60_dom   
Domain families : Pfam (Sanger)M60-like_N (PF17291)    Peptidase_M60 (PF13402)   
Domain families : Pfam (NCBI)pfam17291    pfam13402   
Domain families : Smart (EMBL)M60-like (SM01276)  
Conserved Domain (NCBI)TCAF1
DMDM Disease mutations9747
Blocks (Seattle)TCAF1
SuperfamilyQ9Y4C2
Human Protein Atlas [tissue]ENSG00000198420-TCAF1 [tissue]
Peptide AtlasQ9Y4C2
HPRD13813
IPIIPI00006050   IPI00885016   IPI00004882   IPI01019099   IPI00946974   IPI00946007   IPI00946185   IPI00946727   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4C2
IntAct (EBI)Q9Y4C2
FunCoupENSG00000198420
BioGRIDTCAF1
STRING (EMBL)TCAF1
ZODIACTCAF1
Ontologies - Pathways
QuickGOQ9Y4C2
Ontology : AmiGOprotein binding  plasma membrane  plasma membrane  negative regulation of cell migration  ion channel binding  ion channel binding  ion channel binding  positive regulation of protein targeting to membrane  positive regulation of protein targeting to membrane  positive regulation of anion channel activity  positive regulation of anion channel activity  
Ontology : EGO-EBIprotein binding  plasma membrane  plasma membrane  negative regulation of cell migration  ion channel binding  ion channel binding  ion channel binding  positive regulation of protein targeting to membrane  positive regulation of protein targeting to membrane  positive regulation of anion channel activity  positive regulation of anion channel activity  
NDEx NetworkTCAF1
Atlas of Cancer Signalling NetworkTCAF1
Wikipedia pathwaysTCAF1
Orthology - Evolution
OrthoDB9747
GeneTree (enSembl)ENSG00000198420
Phylogenetic Trees/Animal Genes : TreeFamTCAF1
HOGENOMQ9Y4C2
Homologs : HomoloGeneTCAF1
Homology/Alignments : Family Browser (UCSC)TCAF1
Gene fusions - Rearrangements
Fusion : QuiverTCAF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCAF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCAF1
dbVarTCAF1
ClinVarTCAF1
1000_GenomesTCAF1 
Exome Variant ServerTCAF1
ExAC (Exome Aggregation Consortium)ENSG00000198420
GNOMAD BrowserENSG00000198420
Varsome BrowserTCAF1
Genetic variants : HAPMAP9747
Genomic Variants (DGV)TCAF1 [DGVbeta]
DECIPHERTCAF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCAF1 
Mutations
ICGC Data PortalTCAF1 
TCGA Data PortalTCAF1 
Broad Tumor PortalTCAF1
OASIS PortalTCAF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCAF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCAF1
Mutations and Diseases : HGMDTCAF1
BioMutasearch TCAF1
DgiDB (Drug Gene Interaction Database)TCAF1
DoCM (Curated mutations)TCAF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TCAF1 (select a term)
intoGenTCAF1
Cancer3DTCAF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616251   
Orphanet
DisGeNETTCAF1
MedgenTCAF1
Genetic Testing Registry TCAF1
NextProtQ9Y4C2 [Medical]
TSGene9747
GENETestsTCAF1
Target ValidationTCAF1
Huge Navigator TCAF1 [HugePedia]
snp3D : Map Gene to Disease9747
BioCentury BCIQTCAF1
ClinGenTCAF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9747
Chemical/Pharm GKB GenePA162385749
Clinical trialTCAF1
Miscellaneous
canSAR (ICR)TCAF1 (select the gene name)
DataMed IndexTCAF1
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTCAF1
EVEXTCAF1
GoPubMedTCAF1
iHOPTCAF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:11:07 CET 2019
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