TCEA3 (transcription elongation factor A3)

2016-08-01  

Identity

HGNC
TCEA3
LOCATION
1p36.12
LOCUSID
6920
ALIAS
TFIIS,TFIIS.H
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6920
MIM: 604128
HGNC: 11615
Ensembl: ENSG00000204219

Variants:

dbSNP: 6920
ClinVar: 6920
TCGA: ENSG00000204219
COSMIC: TCEA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204219ENST00000374601O75764
ENSG00000204219ENST00000450454O75764
ENSG00000204219ENST00000461794S4R419
ENSG00000204219ENST00000476978S4R3M9

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
201787422010The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.129
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
233575332013TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells.13
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
270055222016TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene.5
264986642015TCEA3 Attenuates Gastric Cancer Growth by Apoptosis Induction.4

Citation

Dessen P

TCEA3 (transcription elongation factor A3)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55847/tcea3