TCEAL7 (transcription elongation factor A like 7)

2007-02-01  

Identity

HGNC
TCEAL7
LOCATION
Xq22.2
LOCUSID
56849
ALIAS
WEX5

Other Information

Locus ID:

NCBI: 56849
MIM: 300771
HGNC: 28336
Ensembl: ENSG00000182916

Variants:

dbSNP: 56849
ClinVar: 56849
TCGA: ENSG00000182916
COSMIC: TCEAL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182916ENST00000332431Q9BRU2
ENSG00000182916ENST00000372666Q9BRU2

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
158706912005Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer.24
188068252008A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation.18
204545122010TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression.14
199668552010TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway.12
314022742019Hypoxic Glioma Cell-Secreted Exosomal miR-301a Activates Wnt/β-catenin Signaling and Promotes Radiation Resistance by Targeting TCEAL7.9
194197582009Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer.5
194197582009Polymorphisms in TCEAL7 and risk of epithelial ovarian cancer.5
233727502013Decreased expression of transcription elongation factor A-like 7 is associated with gastric adenocarcinoma prognosis.3
313216452019Downregulation of TCEAL7 expression induces CCND1 expression in non-small cell lung cancer.1

Citation

Dessen P

TCEAL7 (transcription elongation factor A like 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43600/tceal7